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- Title
- Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide
- Author(s)
- Y H Kim; S J Choo; In Ja Ryoo; Jong Seog Ahn; Ick-Dong Yoo
- Bibliographic Citation
- Archives of Pharmacal Research, vol. 34, no. 1, pp. 37-41
- Publication Year
- 2011
- Abstract
- A new eudesmanolide, 1β,3β-dihydroxy-eudesman-11(13)-en-6α, 12-olide (1) was isolated and identified from Taraxacum mongolicum, together with two known compounds, 1β,3β-dihydroxyeudesman-6α,12-olide (2) and loliolide (3). The structure of 1 was established by analysis of its physical and spectroscopic data. 1 was found to have an inhibitory activity on nitric oxide production with an IC50 of 38.9 μM in activated RAW 264.7 cells.
- Keyword
- EudesmanolideNitric oxideTaraxacum mongolicumMacrophage
- ISSN
- 0253-6269
- Publisher
- Pharmaceutical Soc Korea
- DOI
- http://dx.doi.org/10.1007/s12272-011-0104-5
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
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