Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide

Cited 16 time in scopus
Metadata Downloads
Title
Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide
Author(s)
Y H Kim; S J Choo; In Ja Ryoo; Jong Seog Ahn; Ick-Dong Yoo
Bibliographic Citation
Archives of Pharmacal Research, vol. 34, no. 1, pp. 37-41
Publication Year
2011
Abstract
A new eudesmanolide, 1β,3β-dihydroxy-eudesman-11(13)-en-6α, 12-olide (1) was isolated and identified from Taraxacum mongolicum, together with two known compounds, 1β,3β-dihydroxyeudesman-6α,12-olide (2) and loliolide (3). The structure of 1 was established by analysis of its physical and spectroscopic data. 1 was found to have an inhibitory activity on nitric oxide production with an IC50 of 38.9 μM in activated RAW 264.7 cells.
Keyword
EudesmanolideNitric oxideTaraxacum mongolicumMacrophage
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/s12272-011-0104-5
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.