Fusarisetin A, an acinar morphogenesis inhibitor from a soil fungus, Fusarium sp. FN080326 = 토양곰팡이 푸사리움 속 FN080326으로부터 분리한 acinar morphogenesis 저해제 푸사리세틴 A

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Title
Fusarisetin A, an acinar morphogenesis inhibitor from a soil fungus, Fusarium sp. FN080326 = 토양곰팡이 푸사리움 속 FN080326으로부터 분리한 acinar morphogenesis 저해제 푸사리세틴 A
Author(s)
JaeHyuik Jang; Y Asami; Jun Pil Jang; Sun Ok Kim; D O Moon; Kee Sun Shin; D Hashizume; M Muroi; T Saito; H Oh; Bo Yeon Kim; H Osada; Jong Seog Ahn
Bibliographic Citation
Journal of American Chemical Society, vol. 133, no. 18, pp. 6865-6867
Publication Year
2011
Abstract
An acinar morphogenesis inhibitor named fusarisetin A (1) that possesses both an unprecedented carbon skeleton and a new pentacyclic ring system has been identified from an in-house fractionated fungal library using a three-dimensional matrigel-induced acinarmorphogenesis assay system. The structure of 1 was determined in detail by NMR and circular dichroism spectroscopy, X-ray analysis, and chemical reaction experiments.
ISSN
0002-7863
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/ja1110688
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
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