Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
A new xanthene from Desmostachya bipinnata (L.) stapf inhibits signal transducer and activator of transcription 3 (STAT3) and low-density lipoprotein-oxidation
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | S Shrestha | - |
| dc.contributor.author | J H Park | - |
| dc.contributor.author | D Y Lee | - |
| dc.contributor.author | J G Cho | - |
| dc.contributor.author | E Cui | - |
| dc.contributor.author | I S Chung | - |
| dc.contributor.author | Byoung-Mog Kwon | - |
| dc.contributor.author | M H Cho | - |
| dc.contributor.author | Tae Sook Jeong | - |
| dc.contributor.author | N I Baek | - |
| dc.date.accessioned | 2017-04-19T09:23:31Z | - |
| dc.date.available | 2017-04-19T09:23:31Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.issn | I000-0171 | - |
| dc.identifier.uri | 10.3839/jksabc.2011.049 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10156 | - |
| dc.description.abstract | A new xanthene was isolated from the methanolic extract of Desmostachya bipinnnata through repeated silica gel and octadecyl silica gel column chromatographies. Based on spectroscopic data including nuclear magnetic resonance, fast atom bombardment mass spectrometry, and infrared spectroscopy, chemical structure of the compound was determined to be 2,6-dihydroxy-7-methoxy-3H-xanthen-3-one. The compound exhibited inhibitions of signal transducer and activator of transcription 3-dependent luciferase activity in HCT-116 colon cancer cell line with IC50 value of 5 μM and low-density lipoprotein-oxidation with IC50 value of 27.2 μM. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | A new xanthene from Desmostachya bipinnata (L.) stapf inhibits signal transducer and activator of transcription 3 (STAT3) and low-density lipoprotein-oxidation | - |
| dc.title.alternative | A new xanthene from Desmostachya bipinnata (L.) stapf inhibits signal transducer and activator of transcription 3 (STAT3) and low-density lipoprotein-oxidation | - |
| dc.type | Article | - |
| dc.citation.title | Journal of Korean Society for Applied Biological Chemistry | - |
| dc.citation.number | 2 | - |
| dc.citation.endPage | 311 | - |
| dc.citation.startPage | 308 | - |
| dc.citation.volume | 54 | - |
| dc.contributor.affiliatedAuthor | Byoung-Mog Kwon | - |
| dc.contributor.affiliatedAuthor | Tae Sook Jeong | - |
| dc.contributor.alternativeName | Shrestha | - |
| dc.contributor.alternativeName | 박지해 | - |
| dc.contributor.alternativeName | 이대영 | - |
| dc.contributor.alternativeName | 조진경 | - |
| dc.contributor.alternativeName | 구은지 | - |
| dc.contributor.alternativeName | 정인식 | - |
| dc.contributor.alternativeName | 권병목 | - |
| dc.contributor.alternativeName | 조문희 | - |
| dc.contributor.alternativeName | 정태숙 | - |
| dc.contributor.alternativeName | 백남인 | - |
| dc.identifier.bibliographicCitation | Journal of Korean Society for Applied Biological Chemistry, vol. 54, no. 2, pp. 308-311 | - |
| dc.identifier.doi | 10.3839/jksabc.2011.049 | - |
| dc.subject.keyword | 2,6-dihydroxy-7-methoxy-3h-xanthen-3-one | - |
| dc.subject.keyword | Desmostatchya bipinnata | - |
| dc.subject.keyword | Low-density lipoprotein-oxidation | - |
| dc.subject.keyword | Signal transducer and activator of transcription | - |
| dc.subject.local | 2,6-dihydroxy-7-methoxy-3h-xanthen-3-one | - |
| dc.subject.local | Desmostatchya bipinnata | - |
| dc.subject.local | low-density lipoprotein oxidation | - |
| dc.subject.local | Low-density lipoprotein-oxidation | - |
| dc.subject.local | Low density lipoprotein-oxidation | - |
| dc.subject.local | Low density lipoptotein (LDL) oxidation | - |
| dc.subject.local | Low-density lipoprotein oxidation | - |
| dc.subject.local | Low density lipoprotein oxidation | - |
| dc.subject.local | Signal transducer and activator of transcription 3 (STAT3) | - |
| dc.subject.local | Signal transducer and activator of transcription | - |
| dc.subject.local | Signal transducer and activator of transcription 3 (Stat3) | - |
| dc.subject.local | STAT 3 | - |
| dc.subject.local | STAT3 | - |
| dc.subject.local | Signal transducer and activator of transcription 3 | - |
| dc.subject.local | Stat3 | - |
| dc.subject.local | Signal transducer and activator of transcription factor 3 (STAT3) | - |
| dc.description.journalClass | N | - |
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