Development of a mouse biomagnetic measurement system by using a high-Tc SQUID magnetometer

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Title
Development of a mouse biomagnetic measurement system by using a high-Tc SQUID magnetometer
Author(s)
I S Kim; S Ahn; Chul Ho Lee; Y H Le
Bibliographic Citation
IEEE Transactions on Applied Superconductivity, vol. 21, no. 3, pp. 493-496
Publication Year
2011
Abstract
We have developed a biomagnetic measurement system for mouse by using high-Tc SQUID magnetometer. The system consists of a high-T c SQUID magnetometer, a table-top magnetically shielded box, and a nonmagnetic dewar with a warm-to-cool distance of about 4 mm. Mice with weights of about 27 g were anesthetized and fixed in supine position on a plastic xyz-stage inside the shield box. The SQUID readout signal was digitized in 24-bit and recorded with sampling rate of 1280 Hz. We carried out a scanning measurement by changing x-and y-position of the subject inside the shield box. Finally, we could obtain clear mouse MCG waveforms of about 20 pT in peak amplitude with well defined P-, QRS-, and T-wave. We demonstrated the high-Tc SQUID magnetometer based biomagnetic measurement system is useful for monitoring mouseMCG signals with sufficient noise-to-signal ratio.
Keyword
Biomagnetic measurementHigh-Tc SQUID magnetometerMagnetocardiographyMouse
ISSN
1051-8223
Publisher
IEEE
DOI
http://dx.doi.org/10.1109/TASC.2010.2094993
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
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