Industrial production of fructooligosaccharides by immobilized cells of Aureobasidium pullulans in a packed bed reactor

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Title
Industrial production of fructooligosaccharides by immobilized cells of Aureobasidium pullulans in a packed bed reactor
Author(s)
K H Jung; S H Bang; Tae Kwang Oh; H J Park
Bibliographic Citation
Biotechnology Letters, vol. 33, no. 8, pp. 1621-1624
Publication Year
2011
Abstract
Continuous production of fructooligosaccharides (FOS) by Aureobasidium pullulans immobilized on calcium alginate beads with a packed bed was investigated at a plant scale reactor. Optimum conditions were with 770 g sucrose/l, being fed at 200 l/h at 50°C which gave a productivity of 180 g FOS/l h. Initial activity was maintained for more than 100 days. The reactor was successfully scaled up to a production scale of 1. 2 m3.
Keyword
Cell immobilizationFructooligosaccharidesFructosyltransferasePacked bed reactor
ISSN
0141-5492
Publisher
Springer
DOI
http://dx.doi.org/10.1007/s10529-011-0606-8
Type
Article
Appears in Collections:
Division of Biomedical Research > Metabolic Regulation Research Center > 1. Journal Articles
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