Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli = 대장균에서 페닐프로판노이드 인공 생합성

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dc.contributor.authorOksik Choi-
dc.contributor.authorC Z Wu-
dc.contributor.authorSun-Young Kang-
dc.contributor.authorJong Seog Ahn-
dc.contributor.authorT B Uhm-
dc.contributor.authorYoung-Soo Hong-
dc.date.accessioned2017-04-19T09:25:17Z-
dc.date.available2017-04-19T09:25:17Z-
dc.date.issued2011-
dc.identifier.issn01694146-
dc.identifier.uri10.1007/s10295-011-0954-3ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/10306-
dc.description.abstractBiological synthesis of plant secondary metabolites has attracted increasing attention due to their proven or assumed beneficial properties and health-promoting effects. Phenylpropanoids are the precursors to a range of important plant metabolites such as the secondary metabolites belonging to the flavonoid/stilbenoid class of compounds. In this study, engineered Escherichia coli containing artificial phenylpropanoid biosynthetic pathways utilizing tyrosine as the initial precursor were established for production of plant-specific metabolites such as ferulic acid, naringenin, and resveratrol. The construction of the artificial pathway utilized tyrosine ammonia lyase and 4-coumarate 3-hydroxylase from Saccharothrix espanaensis, cinnamate/4-coumarate:coenzyme A ligase from Streptomyces coelicolor, caffeic acid O-methyltransferase and chalcone synthase from Arabidopsis thaliana, and stilbene synthase from Arachis hypogaea.-
dc.publisherSpringer-
dc.titleBiosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli = 대장균에서 페닐프로판노이드 인공 생합성-
dc.title.alternativeBiosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli-
dc.typeArticle-
dc.citation.titleJournal of Industrial Microbiology & Biotechnology-
dc.citation.number10-
dc.citation.endPage1665-
dc.citation.startPage1657-
dc.citation.volume38-
dc.contributor.affiliatedAuthorJong Seog Ahn-
dc.contributor.affiliatedAuthorYoung-Soo Hong-
dc.contributor.alternativeName최옥식-
dc.contributor.alternativeName오성주-
dc.contributor.alternativeName강선영-
dc.contributor.alternativeName안종석-
dc.contributor.alternativeName엄태붕-
dc.contributor.alternativeName홍영수-
dc.identifier.bibliographicCitationJournal of Industrial Microbiology & Biotechnology, vol. 38, no. 10, pp. 1657-1665-
dc.identifier.doi10.1007/s10295-011-0954-3-
dc.subject.keywordBiosynthesis-
dc.subject.keywordPhenylpropanoid-
dc.subject.keywordHeterologous expression-
dc.subject.keywordArtiWcial pathway-
dc.subject.localBiosynthesis-
dc.subject.localPhenylpropanoid-
dc.subject.localHeterologous expression-
dc.subject.localArtiWcial pathway-
dc.description.journalClassY-
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Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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