Synthesis and anti-platelet activity of obovatol derivatives
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J H Kwak | - |
| dc.contributor.author | S Lee | - |
| dc.contributor.author | E S Park | - |
| dc.contributor.author | J K In | - |
| dc.contributor.author | J Song | - |
| dc.contributor.author | Y J Kim | - |
| dc.contributor.author | N S Choi | - |
| dc.contributor.author | H Lee | - |
| dc.contributor.author | Y P Yun | - |
| dc.contributor.author | J T Hong | - |
| dc.contributor.author | Young Shin Kwak | - |
| dc.contributor.author | K H Min | - |
| dc.contributor.author | J K Jung | - |
| dc.date.accessioned | 2017-04-19T09:25:26Z | - |
| dc.date.available | 2017-04-19T09:25:26Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.issn | 0253-6269 | - |
| dc.identifier.uri | 10.1007/s12272-011-0708-9 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10340 | - |
| dc.description.abstract | Obovatol derivatives were synthesized and evaluated for anti-platelet activity. Three derivatives (1, 2, 4i) displayed equipotent activity to obovatolin arachidonic acid-induced platelet aggregation. An initial SAR study revealed that the introduction of alkoxy group in B ring could enhance inhibitory activity. | - |
| dc.publisher | Pharmaceutical Soc Korea | - |
| dc.title | Synthesis and anti-platelet activity of obovatol derivatives | - |
| dc.title.alternative | Synthesis and anti-platelet activity of obovatol derivatives | - |
| dc.type | Article | - |
| dc.citation.title | Archives of Pharmacal Research | - |
| dc.citation.number | 7 | - |
| dc.citation.endPage | 1112 | - |
| dc.citation.startPage | 1107 | - |
| dc.citation.volume | 34 | - |
| dc.contributor.affiliatedAuthor | Young Shin Kwak | - |
| dc.contributor.alternativeName | 곽재환 | - |
| dc.contributor.alternativeName | 이설 | - |
| dc.contributor.alternativeName | 박은석 | - |
| dc.contributor.alternativeName | 인진경 | - |
| dc.contributor.alternativeName | 송지호 | - |
| dc.contributor.alternativeName | 김영진 | - |
| dc.contributor.alternativeName | 최남송 | - |
| dc.contributor.alternativeName | 이희순 | - |
| dc.contributor.alternativeName | 윤여표 | - |
| dc.contributor.alternativeName | 홍진태 | - |
| dc.contributor.alternativeName | 곽영신 | - |
| dc.contributor.alternativeName | 민경훈 | - |
| dc.contributor.alternativeName | 정재경 | - |
| dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 34, no. 7, pp. 1107-1112 | - |
| dc.identifier.doi | 10.1007/s12272-011-0708-9 | - |
| dc.subject.keyword | Anti-platelet activity | - |
| dc.subject.keyword | Derivatives | - |
| dc.subject.keyword | Obovatol | - |
| dc.subject.keyword | Small molecules | - |
| dc.subject.local | Anti-platelet activity | - |
| dc.subject.local | Antiplatelet activity | - |
| dc.subject.local | Derivatives | - |
| dc.subject.local | obovatol | - |
| dc.subject.local | Obovatol | - |
| dc.subject.local | small molecule | - |
| dc.subject.local | Small molecules | - |
| dc.subject.local | Small molecule | - |
| dc.description.journalClass | Y | - |
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