Synthesis and anti-platelet activity of obovatol derivatives

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dc.contributor.authorJ H Kwak-
dc.contributor.authorS Lee-
dc.contributor.authorE S Park-
dc.contributor.authorJ K In-
dc.contributor.authorJ Song-
dc.contributor.authorY J Kim-
dc.contributor.authorN S Choi-
dc.contributor.authorH Lee-
dc.contributor.authorY P Yun-
dc.contributor.authorJ T Hong-
dc.contributor.authorYoung Shin Kwak-
dc.contributor.authorK H Min-
dc.contributor.authorJ K Jung-
dc.date.accessioned2017-04-19T09:25:26Z-
dc.date.available2017-04-19T09:25:26Z-
dc.date.issued2011-
dc.identifier.issn0253-6269-
dc.identifier.uri10.1007/s12272-011-0708-9ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/10340-
dc.description.abstractObovatol derivatives were synthesized and evaluated for anti-platelet activity. Three derivatives (1, 2, 4i) displayed equipotent activity to obovatolin arachidonic acid-induced platelet aggregation. An initial SAR study revealed that the introduction of alkoxy group in B ring could enhance inhibitory activity.-
dc.publisherPharmaceutical Soc Korea-
dc.titleSynthesis and anti-platelet activity of obovatol derivatives-
dc.title.alternativeSynthesis and anti-platelet activity of obovatol derivatives-
dc.typeArticle-
dc.citation.titleArchives of Pharmacal Research-
dc.citation.number7-
dc.citation.endPage1112-
dc.citation.startPage1107-
dc.citation.volume34-
dc.contributor.affiliatedAuthorYoung Shin Kwak-
dc.contributor.alternativeName곽재환-
dc.contributor.alternativeName이설-
dc.contributor.alternativeName박은석-
dc.contributor.alternativeName인진경-
dc.contributor.alternativeName송지호-
dc.contributor.alternativeName김영진-
dc.contributor.alternativeName최남송-
dc.contributor.alternativeName이희순-
dc.contributor.alternativeName윤여표-
dc.contributor.alternativeName홍진태-
dc.contributor.alternativeName곽영신-
dc.contributor.alternativeName민경훈-
dc.contributor.alternativeName정재경-
dc.identifier.bibliographicCitationArchives of Pharmacal Research, vol. 34, no. 7, pp. 1107-1112-
dc.identifier.doi10.1007/s12272-011-0708-9-
dc.subject.keywordAnti-platelet activity-
dc.subject.keywordDerivatives-
dc.subject.keywordObovatol-
dc.subject.keywordSmall molecules-
dc.subject.localAnti-platelet activity-
dc.subject.localAntiplatelet activity-
dc.subject.localDerivatives-
dc.subject.localobovatol-
dc.subject.localObovatol-
dc.subject.localsmall molecule-
dc.subject.localSmall molecules-
dc.subject.localSmall molecule-
dc.description.journalClassY-
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