Syntheses of sulfur and selenium analogues of pachastrissamine via double displacements of cyclic sulfate = 고리형 설페이트의 이중 치환을 이용한 파카스크리사민 유도체의 합성

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Title
Syntheses of sulfur and selenium analogues of pachastrissamine via double displacements of cyclic sulfate = 고리형 설페이트의 이중 치환을 이용한 파카스크리사민 유도체의 합성
Author(s)
H Jeon; H Bae; D J Baek; Young Shin Kwak; D Kim; S Kim
Bibliographic Citation
Organic & Biomolecular Chemistry, vol. 9, no. 20, pp. 7237-7242
Publication Year
2011
Abstract
Bioisosteric analogues of pachastrissamine that contain sulfur and selenium atoms replacing the oxygen in the ring system, were efficiently prepared from a cyclic sulfate intermediate by sequential intermolecular and intramolecular S N2 displacement reactions of the dianions. The analogues exhibited cytotoxicities comparable to that of pachastrissamine.
ISSN
1477-0520
Publisher
Royal Soc Chem
DOI
http://dx.doi.org/10.1039/c1ob05920c
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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