Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Bioderived polyelectrolyte nanogels for robust antigen loading and vaccine adjuvant effects
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- Title
- Bioderived polyelectrolyte nanogels for robust antigen loading and vaccine adjuvant effects
- Author(s)
- Y T Lim; Sang-Moo Shim; Y W Noh; K S Lee; D Y Choi; H Uyama; H H Bae; J H Kim; K S Hong; M H Sung; Haryoung Poo
- Bibliographic Citation
- Small, vol. 7, no. 23, pp. 3281-3286
- Publication Year
- 2011
- Abstract
- An easy but robust strategy for the synthesis of bioderived polyelectrolyte nanogels for protein antigen loading and vaccine adjuvant systems that can improve both humoral (Th2) and cellular immunity (Th1) is presented. The synthesized polyelectrolyte nanogels promote the uptake of antigens into antigen-presenting cells and strongly induce ovalbumin-specific INF-γ producing cells, cytotoxic T cell activity, and antibody production.
- ISSN
- 1613-6810
- Publisher
- Wiley
- Full Text Link
- http://dx.doi.org/10.1002/smll.201101836
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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