Open Access@KRIBBDivision of A.I. & Biomedical ResearchOrphan Disease Therapeutic Target Research Center1. Journal Articles
Identification of proteins differentially expressed in gastric cancer cells with high metastatic potential for invasion to lymph nodes
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | D H Lee | - |
| dc.contributor.author | Youra Lee | - |
| dc.contributor.author | Joohyun Ryu | - |
| dc.contributor.author | Sung Goo Park | - |
| dc.contributor.author | S Cho | - |
| dc.contributor.author | J J Lee | - |
| dc.contributor.author | C Choi | - |
| dc.contributor.author | Byoung Chul Park | - |
| dc.date.accessioned | 2017-04-19T09:28:16Z | - |
| dc.date.available | 2017-04-19T09:28:16Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.issn | 1016-8478 | - |
| dc.identifier.uri | 10.1007/s10059-011-1053-z | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10535 | - |
| dc.description.abstract | In a search for proteins involved in cancer metastasis, we analyzed proteomes of the human gastric cancer cell OCUM-2M and its metastatic subline OCUM-2MLN. We observed that aspartate aminotransferase (AAT), D-site binding protein (DBP), and anterior gradient protein 2 (AGR2) are differentially expressed in metastatic OCUM-2MLN cells. Measurement of protein expression in clinical samples indicated that DBP and AAT are also down-regulated in metastatic adenocarcinoma. Additionally, urokinase-type tissue plasminogen activator is up-regulated in OCUM-2MLN cells and also in metastatic gastric cancer samples. Collectively, these results raise a possibility that AAT, DBP and AGR2 are functionally implicated in the invasiveness of gastric cancer cells. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | Identification of proteins differentially expressed in gastric cancer cells with high metastatic potential for invasion to lymph nodes | - |
| dc.title.alternative | Identification of proteins differentially expressed in gastric cancer cells with high metastatic potential for invasion to lymph nodes | - |
| dc.type | Article | - |
| dc.citation.title | Molecules and Cells | - |
| dc.citation.number | 6 | - |
| dc.citation.endPage | 571 | - |
| dc.citation.startPage | 563 | - |
| dc.citation.volume | 31 | - |
| dc.contributor.affiliatedAuthor | Youra Lee | - |
| dc.contributor.affiliatedAuthor | Joohyun Ryu | - |
| dc.contributor.affiliatedAuthor | Sung Goo Park | - |
| dc.contributor.affiliatedAuthor | Byoung Chul Park | - |
| dc.contributor.alternativeName | 이도희 | - |
| dc.contributor.alternativeName | 이유라 | - |
| dc.contributor.alternativeName | 유주현 | - |
| dc.contributor.alternativeName | 박성구 | - |
| dc.contributor.alternativeName | 조사연 | - |
| dc.contributor.alternativeName | 이제정 | - |
| dc.contributor.alternativeName | 최찬 | - |
| dc.contributor.alternativeName | 박병철 | - |
| dc.identifier.bibliographicCitation | Molecules and Cells, vol. 31, no. 6, pp. 563-571 | - |
| dc.identifier.doi | 10.1007/s10059-011-1053-z | - |
| dc.subject.keyword | AAT | - |
| dc.subject.keyword | AGR2 | - |
| dc.subject.keyword | DBP | - |
| dc.subject.keyword | gastric cancer | - |
| dc.subject.keyword | metastasis | - |
| dc.subject.keyword | proteome | - |
| dc.subject.local | AAT | - |
| dc.subject.local | AGR2 | - |
| dc.subject.local | DBP | - |
| dc.subject.local | Gastric cancer | - |
| dc.subject.local | Gastric cancer (GC) | - |
| dc.subject.local | gastric cancer | - |
| dc.subject.local | Gastric Cancer | - |
| dc.subject.local | metastasis | - |
| dc.subject.local | Metastasis | - |
| dc.subject.local | Proteome | - |
| dc.subject.local | Proteomes | - |
| dc.subject.local | proteome | - |
| dc.description.journalClass | Y | - |
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Critical Diseases Diagnostics Convergence Research Center > 1. Journal Articles
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