Azuki bean (Vigna angularis) extract inhibits the development of experimentally induced atopic dermatitis-like skin lesions in NC/Nga mice

Cited 10 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorT M Collantes-
dc.contributor.authorMun Chual Rho-
dc.contributor.authorKwon Hyung Jun-
dc.contributor.authorB G Jung-
dc.contributor.authorM M Alfajaro-
dc.contributor.authorD S Kim-
dc.contributor.authorH J Kim-
dc.contributor.authorM Hosmillo-
dc.contributor.authorJ G Park-
dc.contributor.authorK Y Son-
dc.contributor.authorS I Park-
dc.contributor.authorM I Kang-
dc.contributor.authorSu-Jin Park-
dc.contributor.authorSeung Woong Lee-
dc.contributor.authorWoo Song Lee-
dc.contributor.authorK O Cho-
dc.date.accessioned2017-04-19T09:28:26Z-
dc.date.available2017-04-19T09:28:26Z-
dc.date.issued2012-
dc.identifier.issn0308-8146-
dc.identifier.uri10.1016/j.foodchem.2011.11.100ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/10548-
dc.description.abstractThe present study investigated the effects of azuki bean (Vigna angularis) extract (VAE) on the progress of atopic dermatitis (AD)-like skin lesions in NC/Nga mice induced by 1-chloro-2,4-dinitrobenzene. The efficacy of VAE in NC/Nga mice was determined by measuring gross and histological skin lesions, serum IgE levels, eosinophil ratio in peripheral leucocytes, and mRNA expression levels of interleukin (IL)-4, tumour necrosis factor (TNF)-α and interferon (IFN)-γ in splenocytes. Continuous ingestion of VAE inhibited the development of the AD-like skin lesions in a dose-dependent manner. In the VAE-treated mice, the numbers of mast cells in the skin, eosinophil ratio in peripheral leucocytes, relative mRNA expression of inflammatory cytokines in the spleen, and serum IgE levels were significantly reduced. Results suggest that VAE can inhibit the development of AD-like skin lesions in NC/Nga mice by regulating immune mediators and cells, and may be an effective alternative therapy for AD.-
dc.publisherElsevier-
dc.titleAzuki bean (Vigna angularis) extract inhibits the development of experimentally induced atopic dermatitis-like skin lesions in NC/Nga mice-
dc.title.alternativeAzuki bean (Vigna angularis) extract inhibits the development of experimentally induced atopic dermatitis-like skin lesions in NC/Nga mice-
dc.typeArticle-
dc.citation.titleFood Chemistry-
dc.citation.number3-
dc.citation.endPage1275-
dc.citation.startPage1269-
dc.citation.volume132-
dc.contributor.affiliatedAuthorMun Chual Rho-
dc.contributor.affiliatedAuthorKwon Hyung Jun-
dc.contributor.affiliatedAuthorSu-Jin Park-
dc.contributor.affiliatedAuthorSeung Woong Lee-
dc.contributor.affiliatedAuthorWoo Song Lee-
dc.contributor.alternativeNameCollantes-
dc.contributor.alternativeName노문철-
dc.contributor.alternativeName권형준-
dc.contributor.alternativeName정복기-
dc.contributor.alternativeNameAlfajaro-
dc.contributor.alternativeName김덕송-
dc.contributor.alternativeName김현정-
dc.contributor.alternativeNameHosmillo-
dc.contributor.alternativeName박준규-
dc.contributor.alternativeName손규열-
dc.contributor.alternativeName박상익-
dc.contributor.alternativeName강문일-
dc.contributor.alternativeName박수진-
dc.contributor.alternativeName이승웅-
dc.contributor.alternativeName이우송-
dc.contributor.alternativeName조경오-
dc.identifier.bibliographicCitationFood Chemistry, vol. 132, no. 3, pp. 1269-1275-
dc.identifier.doi10.1016/j.foodchem.2011.11.100-
dc.subject.keywordAtopic dermatitis-
dc.subject.keywordAzuki bean-
dc.subject.keywordIgE-
dc.subject.keywordImmune cells-
dc.subject.keywordInflammatory cytokines-
dc.subject.keywordNC/Nga mice-
dc.subject.localAtopic Dermatitis-
dc.subject.localAtopic dermatitis-
dc.subject.localatopic dermatitis (AD)-
dc.subject.localatopic dermatitis-
dc.subject.localAzuki bean-
dc.subject.localIgE-
dc.subject.localImmune Cells-
dc.subject.localimmune cell-
dc.subject.localimmune cells-
dc.subject.localImmune cells-
dc.subject.localImmune cell-
dc.subject.localInflammatory cytokines-
dc.subject.localInflammatory cytokine-
dc.subject.localinflammatory cytokines-
dc.subject.localNC/Nga mice-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Functional Biomaterial Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.