Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375 = Penicillium verruculosum이 생산하는 새로운 항세균 enoyl-ACP reductase 저해물질
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Nyung Kim | - |
| dc.contributor.author | M J Sohn | - |
| dc.contributor.author | Chang-Jin Kim | - |
| dc.contributor.author | H J Kwon | - |
| dc.contributor.author | Won Gon Kim | - |
| dc.date.accessioned | 2017-04-19T09:28:54Z | - |
| dc.date.available | 2017-04-19T09:28:54Z | - |
| dc.date.issued | 2012 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.uri | 10.1016/j.bmcl.2012.02.001 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10616 | - |
| dc.description.abstract | New dimeric compounds of alternariol class, verrulactones A and B, were isolated from a culture broth of the fungal strain Penicillium verruculosum F375 and their structure were established by various spectral analysis. Verrulactones A and B strongly inhibited Staphylococcus aureus enoyl-ACP reductase with IC 50 of 0.92 and 1.41 μM, respectively, and also showed antibacterial activity against S. aureus and MRSA with MICs of 8 and 16 μg/mL, respectively. | - |
| dc.publisher | Elsevier | - |
| dc.title | Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375 = Penicillium verruculosum이 생산하는 새로운 항세균 enoyl-ACP reductase 저해물질 | - |
| dc.title.alternative | Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375 | - |
| dc.type | Article | - |
| dc.citation.title | Bioorganic & Medicinal Chemistry Letters | - |
| dc.citation.number | 7 | - |
| dc.citation.endPage | 2506 | - |
| dc.citation.startPage | 2503 | - |
| dc.citation.volume | 22 | - |
| dc.contributor.affiliatedAuthor | Nyung Kim | - |
| dc.contributor.affiliatedAuthor | Chang-Jin Kim | - |
| dc.contributor.affiliatedAuthor | Won Gon Kim | - |
| dc.contributor.alternativeName | 김녕 | - |
| dc.contributor.alternativeName | 손미진 | - |
| dc.contributor.alternativeName | 김창진 | - |
| dc.contributor.alternativeName | 권호정 | - |
| dc.contributor.alternativeName | 김원곤 | - |
| dc.identifier.bibliographicCitation | Bioorganic & Medicinal Chemistry Letters, vol. 22, no. 7, pp. 2503-2506 | - |
| dc.identifier.doi | 10.1016/j.bmcl.2012.02.001 | - |
| dc.subject.keyword | Enoyl-ACP reductase | - |
| dc.subject.keyword | FabI | - |
| dc.subject.keyword | Inhibitor | - |
| dc.subject.keyword | Penicillium verruculosum | - |
| dc.subject.keyword | Staphylococcus aureus | - |
| dc.subject.local | Enoyl-ACP reductase | - |
| dc.subject.local | enoyl-ACP reductase | - |
| dc.subject.local | FabI | - |
| dc.subject.local | inhibitors | - |
| dc.subject.local | Inhibitors | - |
| dc.subject.local | inhibitor | - |
| dc.subject.local | Inhibitor | - |
| dc.subject.local | Penicillium verruculosum | - |
| dc.subject.local | Staphylococcus aureus | - |
| dc.subject.local | staphylococcus aureus | - |
| dc.description.journalClass | Y | - |
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