Self-fluorescence of chemically crosslinked MRI nanoprobes to enable multimodal imaging of therapeutic cells
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Title
Self-fluorescence of chemically crosslinked MRI nanoprobes to enable multimodal imaging of therapeutic cells
Author(s)
H M Kim; Y W Noh; H S Park; M Y Cho; K S Hong; H Lee; D H Shin; J Kang; M H Sung; Haryoung Poo; Y T Lim
Bibliographic Citation
Small, vol. 8, no. 5, pp. 666-670
Publication Year
2012
Abstract
Old chemistry for novel materials: Self-fluorescent high-relaxivity T 2-weighted magnetic resonance imaging (MRI) contrast agents are produced. They are a novel type of MR/optical dual-modality in vivo imaging nanoprobe using glutaraldehyde crosslinking chemistry, and they are used to label and monitor therapeutic cells both in vitro and in vivo.