Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets = 미세 유체액적 기술과 재설계 유전자회로를 이용한 신규활성 미생물 탐색

Abstract

We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Each droplet in the array forms a stable environment of pico-litre volume to implement a single-cell-based assay.