DC Field | Value | Language |
---|---|---|
dc.contributor.author | Y H Kim | - |
dc.contributor.author | Soo-Jin Choo | - |
dc.contributor.author | In Ja Ryoo | - |
dc.contributor.author | Bo Yeon Kim | - |
dc.contributor.author | Jong Seog Ahn | - |
dc.contributor.author | Ick-Dong Yoo | - |
dc.date.accessioned | 2017-04-19T09:30:03Z | - |
dc.date.available | 2017-04-19T09:30:03Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | 10.4014/jmb.1101.01053 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10716 | - |
dc.description.abstract | In the continued search for melanogenesis inhibitors from microbial metabolites, we found that the culture broth of Clitocybe sp. MKACC 53267 inhibited melanogenesis in B16F10 melanoma cells. The active component was purified by solvent extraction, silica gel chromatography, Sephadex LH-20 column chromatography, and finally by preparative HPLC. Its structure was determined as 5-pentyl-2-furaldehyde on the basis of the UV, NMR, and MS spectroscopic analysis. The 5-pentyl-2-furaldehyde potently inhibited melanogenesis in B16F10 cells with an IC 50 value of 8.4 μg/ml, without cytotoxicity. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | Inhibitory effect of melanogenesis by 5-pentyl-2-furaldehyde isolated from Clitocybe sp. | - |
dc.title.alternative | Inhibitory effect of melanogenesis by 5-pentyl-2-furaldehyde isolated from Clitocybe sp. | - |
dc.type | Article | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.number | 6 | - |
dc.citation.endPage | 817 | - |
dc.citation.startPage | 814 | - |
dc.citation.volume | 22 | - |
dc.contributor.affiliatedAuthor | Soo-Jin Choo | - |
dc.contributor.affiliatedAuthor | In Ja Ryoo | - |
dc.contributor.affiliatedAuthor | Bo Yeon Kim | - |
dc.contributor.affiliatedAuthor | Jong Seog Ahn | - |
dc.contributor.affiliatedAuthor | Ick-Dong Yoo | - |
dc.contributor.alternativeName | 김영희 | - |
dc.contributor.alternativeName | 추수진 | - |
dc.contributor.alternativeName | 류인자 | - |
dc.contributor.alternativeName | 김보연 | - |
dc.contributor.alternativeName | 안종석 | - |
dc.contributor.alternativeName | 유익동 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, vol. 22, no. 6, pp. 814-817 | - |
dc.identifier.doi | 10.4014/jmb.1101.01053 | - |
dc.subject.keyword | 5-penty 1-2-furaldehyde | - |
dc.subject.keyword | B16F10 melanoma | - |
dc.subject.keyword | Clitocybe sp | - |
dc.subject.keyword | Melanogenesis | - |
dc.subject.local | 5-penty 1-2-furaldehyde | - |
dc.subject.local | B16F10 melanoma | - |
dc.subject.local | Clitocybe sp | - |
dc.subject.local | melanogenesis | - |
dc.subject.local | Melanogenesis | - |
dc.description.journalClass | Y | - |
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