Effects of fenvalerate on apoptosis level and GFAP expression in the brain tissue of the pale chub = Fenvalerate가 피라미(Zacco platypus) 뇌 조직에서 apoptosis 정도와 GFAP 발현에 미치는 영향

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dc.contributor.authorS W Kim-
dc.contributor.authorN K Park-
dc.contributor.authorSang Rae Lee-
dc.contributor.authorD S Reu-
dc.date.accessioned2017-04-19T09:32:10Z-
dc.date.available2017-04-19T09:32:10Z-
dc.date.issued2012-
dc.identifier.issn1225-6773-
dc.identifier.uri10.9729/AM.2012.42.2.053ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/10806-
dc.description.abstractWe evaluated the level of toxicity by LC50 and investigated the mechanism of brain impairment and GFAP expression by light and fluorescence microscopes in the pale chub, Zacco platypus, treated with fenvalerate. Survival rate was decreased according to the rise of fenvalerate concentration, and LC50 concentration was 27.79 μg/L. Apoptosis was increased according to the rise of fenvalerate concentration by TUNEL assay which determine apoptotic cell death population. Also, GFAP expression was increased in the periventricular zone. These results suggest that apoptosis might be a major mechanism to brain impairment of the pale chub by fenvalrerate. Increased GFAP expression in the periventricular zone would be an index of brain impairment. Taken together, this study might contribute to reveal the pathological mechanism of fish brain impairment by insecticide of pyrethroid, and to be an useful basic data for preservation of aquatic ecosystem.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleEffects of fenvalerate on apoptosis level and GFAP expression in the brain tissue of the pale chub = Fenvalerate가 피라미(Zacco platypus) 뇌 조직에서 apoptosis 정도와 GFAP 발현에 미치는 영향-
dc.title.alternativeEffects of fenvalerate on apoptosis level and GFAP expression in the brain tissue of the pale chub-
dc.typeArticle-
dc.citation.titleKorean Journal of Microscopy-
dc.citation.number2-
dc.citation.endPage59-
dc.citation.startPage53-
dc.citation.volume42-
dc.contributor.affiliatedAuthorSang Rae Lee-
dc.contributor.alternativeName김성우-
dc.contributor.alternativeName박노관-
dc.contributor.alternativeName이상래-
dc.contributor.alternativeName류동석-
dc.identifier.bibliographicCitationKorean Journal of Microscopy, vol. 42, no. 2, pp. 53-59-
dc.identifier.doi10.9729/AM.2012.42.2.053-
dc.subject.keywordApoptosis-
dc.subject.keywordBrain-
dc.subject.keywordFenvalerate-
dc.subject.keywordGFAP-
dc.subject.keywordZacco platypus-
dc.subject.localapoptosis-
dc.subject.localApoptosis-
dc.subject.localBrain-
dc.subject.localbrain-
dc.subject.localFenvalerate-
dc.subject.localGFAP-
dc.subject.localZacco platypus-
dc.description.journalClassN-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > National Primate Research Center > 1. Journal Articles
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