DC Field | Value | Language |
---|---|---|
dc.contributor.author | S Lee | - |
dc.contributor.author | J S Ha | - |
dc.contributor.author | Seung Goo Lee | - |
dc.contributor.author | T K Kim | - |
dc.date.accessioned | 2017-04-19T09:32:17Z | - |
dc.date.available | 2017-04-19T09:32:17Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | 10.1021/ja303518d | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10822 | - |
dc.description.abstract | We present a novel phenotypic readout using inducible, biosynthetic nanoscaffolds to directly visualize dynamic molecular interactions within living cells at the single-cell level with high sensitivity and selectivity. Labeled ferritin is used to form biological nanoparticles inside cells. Specific supramolecular assembly of ferritin-derived nanoparticles induces highly clustered nanoscaffolds. These inducible biosynthetic nanoscaffolds are used as the artificial recruitment/redistribution platform for monitoring interactions of a small molecule with its target protein(s) inside living cells. | - |
dc.publisher | Amer Chem Soc | - |
dc.title | Inducible biosynthetic nanoscaffolds as recruitment platforms for detecting molecular target interactions inside living cells = 세포내 상호작용 감지를 위한 나노 플랫폼 | - |
dc.title.alternative | Inducible biosynthetic nanoscaffolds as recruitment platforms for detecting molecular target interactions inside living cells | - |
dc.type | Article | - |
dc.citation.title | Journal of American Chemical Society | - |
dc.citation.number | 28 | - |
dc.citation.endPage | 11349 | - |
dc.citation.startPage | 11346 | - |
dc.citation.volume | 134 | - |
dc.contributor.affiliatedAuthor | Seung Goo Lee | - |
dc.contributor.alternativeName | 이상규 | - |
dc.contributor.alternativeName | 하재석 | - |
dc.contributor.alternativeName | 이승구 | - |
dc.contributor.alternativeName | 김태국 | - |
dc.identifier.bibliographicCitation | Journal of American Chemical Society, vol. 134, no. 28, pp. 11346-11349 | - |
dc.identifier.doi | 10.1021/ja303518d | - |
dc.description.journalClass | Y | - |
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