Anti-hyperlipidemic effect of the isolated component, quercetin-3-O-rhamnoside and the fractions from the extract of Houttuynia cordata in mice = Poloxamer-407로 유도한 고지혈증 동물모델에서 Quercetin-3-O-rhamnoside 및 어성초 분획물의 항고지혈증 효과

Abstract

The anti-hyperlipidemic effects of Houttuynia cordata were assessed in poloxamer-404 induced hyperlipidemic mice model. The butanol fraction and its isolated compound, quercetin-3-α·-O-rhamnoside, significantly educed the blood triglyceride and total-cholesterol level and increased the blood HDL-cholesterol level. They also show the significant reductive effect on the blood AST and ALT level, rising in propotion to the liver damage, in hyperlipidemic mice.