Graphene-oxide-based immunosensing through fluorescence quenching by peroxidase-catalyzed polymerization

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Title
Graphene-oxide-based immunosensing through fluorescence quenching by peroxidase-catalyzed polymerization
Author(s)
S Y Lim; Junhyoung Ahn; J S Lee; M G Kim; C B Park
Bibliographic Citation
Small, vol. 8, no. 13, pp. 1994-1999
Publication Year
2012
Abstract
A graphene oxide (GO)-based immunosensor is developed for the detection of interleukin-5 (IL-5), a key cytokine associated with asthma pathology and eosinophilia. The immunosensing platform utilizes the innate fluorescence of GO, not demanding biomolecules labeled with fluorescent dyes. The GO-based immunoassay exhibits high specificity for IL-5 among other cytokines and is not affected by nonspecific proteins in human serum.
Keyword
biosensorscytokinesfluorescencegraphene oxidenanotechnology
ISSN
1613-6810
Publisher
Wiley
DOI
http://dx.doi.org/10.1002/smll.201200379
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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