Palladium-catalyzed arylation of alpha,beta-unsaturated Weinreb amides

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Title
Palladium-catalyzed arylation of alpha,beta-unsaturated Weinreb amides
Author(s)
K H Kim; Sangku Lee; S H Kim; C H Lim; J N Kim
Bibliographic Citation
Tetrahedron Letters, vol. 53, no. 38, pp. 5088-5093
Publication Year
2012
Abstract
Palladium-catalyzed arylation of α,β-unsaturated Weinreb amides has been examined to obtain β-aryl-α,β-unsaturated Weinreb amides. The chelation between the palladium center of an alkylpalladium intermediate and Weinreb amide moiety facilitated both coordination and insertion steps.
Keyword
ArylationChelationPalladiumWeinreb amides
ISSN
0040-4039
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/j.tetlet.2012.07.023
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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