DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hyuk Hwan Song | - |
dc.contributor.author | Hee Sung Chae | - |
dc.contributor.author | Sei Ryang Oh | - |
dc.contributor.author | Hyeong Kyu Lee | - |
dc.contributor.author | Y W Chin | - |
dc.date.accessioned | 2017-04-19T09:33:10Z | - |
dc.date.available | 2017-04-19T09:33:10Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0192-415X | - |
dc.identifier.uri | 10.1142/S0192415X12500796 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10879 | - |
dc.description.abstract | In this study, the anti-inflammatory and anti-allergic effects of the chloroform-soluble extract of Agaricus blazei in mouse bone marrow-derived mast cells (BMMCs) were investigated. The chloroform-soluble extract inhibited IL-6 production in PMA plus A23187-stimulated BMMCs, and down-regulated the phosphorylation of Akt. In addition, this extract demonstrated inhibition of the degranulation of β-hexosaminidase and the production of IL-6, prostaglandin D 2 and leukotriene C 4 in PMA plus A23187-induced BMMCs. In conclusion, the chloroform-soluble extract of Agaricus blazei exerted anti-inflammatory and anti-allergic activities mediated by influencing IL-6, prostaglandin D 2, leukotriene C 4, and the phosphorylation of Akt. | - |
dc.publisher | World Scientific Publ Co Pte Ltd | - |
dc.title | Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells | - |
dc.title.alternative | Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells | - |
dc.type | Article | - |
dc.citation.title | American Journal of Chinese Medicine | - |
dc.citation.number | 5 | - |
dc.citation.endPage | 1084 | - |
dc.citation.startPage | 1073 | - |
dc.citation.volume | 40 | - |
dc.contributor.affiliatedAuthor | Hyuk Hwan Song | - |
dc.contributor.affiliatedAuthor | Hee Sung Chae | - |
dc.contributor.affiliatedAuthor | Sei Ryang Oh | - |
dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
dc.contributor.alternativeName | 송혁환 | - |
dc.contributor.alternativeName | 채희성 | - |
dc.contributor.alternativeName | 오세량 | - |
dc.contributor.alternativeName | 이형규 | - |
dc.contributor.alternativeName | 진영원 | - |
dc.identifier.bibliographicCitation | American Journal of Chinese Medicine, vol. 40, no. 5, pp. 1073-1084 | - |
dc.identifier.doi | 10.1142/S0192415X12500796 | - |
dc.subject.keyword | Agaricus blazei | - |
dc.subject.keyword | Akt | - |
dc.subject.keyword | Bone Marrow Derived Mast Cell | - |
dc.subject.keyword | Degranulation | - |
dc.subject.keyword | Interleukin-6 | - |
dc.subject.keyword | Leukotriene C 4 | - |
dc.subject.keyword | Prostaglandin D 2 | - |
dc.subject.local | agaricus blazei | - |
dc.subject.local | Agaricus blazei | - |
dc.subject.local | AKT | - |
dc.subject.local | Akt | - |
dc.subject.local | Bone marrow-derived mast cell | - |
dc.subject.local | Bone Marrow Derived Mast Cell | - |
dc.subject.local | bone-marrow derived mast cell | - |
dc.subject.local | Bone marrow derived mast cell | - |
dc.subject.local | Degranulation | - |
dc.subject.local | IL6 | - |
dc.subject.local | interukin -6 | - |
dc.subject.local | Interleukin-6 (IL-6) | - |
dc.subject.local | IL-6 | - |
dc.subject.local | Il-6 | - |
dc.subject.local | interleukin-6 | - |
dc.subject.local | interleukin-6 (IL-6) | - |
dc.subject.local | Interleukin-6 | - |
dc.subject.local | Leukotriene C4 | - |
dc.subject.local | Leukotriene C 4 | - |
dc.subject.local | leukotriene C4 | - |
dc.subject.local | prostaglandin D2 | - |
dc.subject.local | Prostaglandin D2 | - |
dc.subject.local | Prostaglandin D 2 | - |
dc.description.journalClass | Y | - |
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