Complete genome sequence of a mammalian species-infectious and -pathogenic H6N5 avian influenza virus without evidence of adaptation

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Title
Complete genome sequence of a mammalian species-infectious and -pathogenic H6N5 avian influenza virus without evidence of adaptation
Author(s)
Seong-Jun Park; B K Park; Dae Sub Song; Haryoung Poo
Bibliographic Citation
Journal of Virology, vol. 86, no. 22, pp. 12459-12460
Publication Year
2012
Abstract
An H6N5 avian influenza virus (AIV) strain, designated A/aquatic bird/Korea/CN5/2009 (H6N5), was isolated from fecal swabs of aquatic birds in 2009, and surprisingly, it showed infectivity and pathogenicity in mammalian species withoutevidence of adaptation. In this study, we report the first complete genome sequence containing 3'and 5'noncoding regions(NCRs) of a mammalian species-infectious and pathogenic H6N5 AIV, which will help provide important insights into themolecular basis of pathogenesis, transmission, and evolution of AIV.
ISSN
0022-538X
Publisher
Amer Soc Microb
DOI
http://dx.doi.org/10.1128/JVI.02301-12
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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