DC Field | Value | Language |
---|---|---|
dc.contributor.author | M Kinger | - |
dc.contributor.author | Y D Park | - |
dc.contributor.author | J H Park | - |
dc.contributor.author | M G Hur | - |
dc.contributor.author | Hyung Jae Jung | - |
dc.contributor.author | Su-Jin Park | - |
dc.contributor.author | Woo Song Lee | - |
dc.contributor.author | S W Kim | - |
dc.contributor.author | S D Yang | - |
dc.date.accessioned | 2017-04-19T09:34:23Z | - |
dc.date.available | 2017-04-19T09:34:23Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0253-6269 | - |
dc.identifier.uri | 10.1007/s12272-012-0406-2 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/10976 | - |
dc.description.abstract | A series of 1,3-diarylprop-2-en-1-one derivatives 3a-v have been synthesized and evaluated for their ability to inhibit neuraminidase (NA). Among the prepared compounds, the less lipophilic derivative 3k showed the most potent in vitro inhibitory activity against NA with an IC50 value of 1.5 μM. | - |
dc.publisher | Pharmaceutical Soc Korea | - |
dc.title | Design, synthesis, and anti-influenza viral activities of 1,3-diarylprop-2-en-1-ones: a novel class of neuraminidase inhibitors | - |
dc.title.alternative | Design, synthesis, and anti-influenza viral activities of 1,3-diarylprop-2-en-1-ones: a novel class of neuraminidase inhibitors | - |
dc.type | Article | - |
dc.citation.title | Archives of Pharmacal Research | - |
dc.citation.number | 4 | - |
dc.citation.endPage | 638 | - |
dc.citation.startPage | 633 | - |
dc.citation.volume | 35 | - |
dc.contributor.affiliatedAuthor | Hyung Jae Jung | - |
dc.contributor.affiliatedAuthor | Su-Jin Park | - |
dc.contributor.affiliatedAuthor | Woo Song Lee | - |
dc.contributor.alternativeName | Kinger | - |
dc.contributor.alternativeName | 박용대 | - |
dc.contributor.alternativeName | 박정훈 | - |
dc.contributor.alternativeName | 허민구 | - |
dc.contributor.alternativeName | 정형재 | - |
dc.contributor.alternativeName | 박수진 | - |
dc.contributor.alternativeName | 이우송 | - |
dc.contributor.alternativeName | 김상욱 | - |
dc.contributor.alternativeName | 양승대 | - |
dc.identifier.bibliographicCitation | Archives of Pharmacal Research, vol. 35, no. 4, pp. 633-638 | - |
dc.identifier.doi | 10.1007/s12272-012-0406-2 | - |
dc.subject.keyword | 1,3-Diarylprop-2-en-1-ones | - |
dc.subject.keyword | Anti-influenza activity | - |
dc.subject.keyword | Neuraminidase | - |
dc.subject.keyword | Synthesis | - |
dc.subject.local | 1,3-Diarylprop-2-en-1-ones | - |
dc.subject.local | Anti-influenza activity | - |
dc.subject.local | neuraminidase | - |
dc.subject.local | Neuraminidase | - |
dc.subject.local | synthesis | - |
dc.subject.local | Synthesis | - |
dc.subject.local | synthesis (chemical) | - |
dc.description.journalClass | Y | - |
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