Direct lineage reprogramming to neural cells = 신경계 세포로의 직접적인 계통 리프로그래밍(교차분화)

Cited 37 time in scopus
Metadata Downloads
Title
Direct lineage reprogramming to neural cells = 신경계 세포로의 직접적인 계통 리프로그래밍(교차분화)
Author(s)
Janghwan Kim; R Ambasudhan; S Ding
Bibliographic Citation
Current Opinion in Neurobiology, vol. 22, no. 5, pp. 778-784
Publication Year
2012
Abstract
Recently we have witnessed an array of studies on direct reprogramming that describe induced inter conversion of mature cell types from higher organisms including human. While these studies reveal an unexpected level of plasticity of differentiated somatic cells, they also provide unprecedented opportunities to develop regenerative therapies for many debilitating disorders and model these 'diseases-in-a-dish' for studying their pathophysiology. Here we review the current state of the art in direct lineage reprogramming to neural cells, and discuss the challenges that need to be addressed toward achieving the full potential of this exciting new technology.
ISSN
0959-4388
Publisher
Current Biology Ltd
DOI
http://dx.doi.org/10.1016/j.conb.2012.05.001
Type
Article
Appears in Collections:
Division of Research on National Challenges > Stem Cell Convergenece Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.