Structure and catalytic mechanism of human protein tyrosine phosphatome

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dc.contributor.authorSeung Jun Kim-
dc.contributor.authorS E Ryu-
dc.date.accessioned2017-04-19T09:35:59Z-
dc.date.available2017-04-19T09:35:59Z-
dc.date.issued2012-
dc.identifier.issn1225-8687-
dc.identifier.uri10.5483/BMBRep.2012.45.12.240ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11112-
dc.description.abstractTogether with protein tyrosine kinases (PTKs), protein tyrosine phosphatases (PTPs) serve ashallmarks in cellular signal transduction by controlling the reversible phosphorylationof their substrates. The human genome is estimated to encode more than 100 PTPs, which can be divided into eleven sub-groups according to their structural and functional characteristics. All the crystal structures of catalytic domains of sub-groups have been elucidated, enablingus to understand their precise catalytic mechanism and to compare their structures across all sub-groups. In this review, I describe the structure and mechanism of catalytic domains of PTPs in the structural context.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleStructure and catalytic mechanism of human protein tyrosine phosphatome-
dc.title.alternativeStructure and catalytic mechanism of human protein tyrosine phosphatome-
dc.typeArticle-
dc.citation.titleBMB Reports-
dc.citation.number12-
dc.citation.endPage699-
dc.citation.startPage693-
dc.citation.volume45-
dc.contributor.affiliatedAuthorSeung Jun Kim-
dc.contributor.alternativeName김승준-
dc.contributor.alternativeName류성언-
dc.identifier.bibliographicCitationBMB Reports, vol. 45, no. 12, pp. 693-699-
dc.identifier.doi10.5483/BMBRep.2012.45.12.240-
dc.subject.keywordClassical PTP-
dc.subject.keywordCrystal structure-
dc.subject.keywordDual specificity PTP-
dc.subject.keywordEyes absent-
dc.subject.keywordProtein tyrosine phosphatase(PTP)-
dc.subject.localClassical PTP-
dc.subject.localcrystal structure-
dc.subject.localCrystal structure-
dc.subject.localDual specificity PTP-
dc.subject.localEyes absent-
dc.subject.localProtein tyrosine phosphatase(PTP)-
dc.description.journalClassY-
Appears in Collections:
Critical Diseases Diagnostics Convergence Research Center > 1. Journal Articles
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