Bifunctional nanoparticles constructed using one-pot encapsulation of a fluorescent polymer and magnetic (Fe3O4) nanoparticles in a silica shell

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dc.contributor.authorChang-Soo Lee-
dc.contributor.authorH H Chang-
dc.contributor.authorPan Kee Bae-
dc.contributor.authorJuyeon Jung-
dc.contributor.authorBong Hyun Chung-
dc.date.accessioned2017-04-19T09:39:30Z-
dc.date.available2017-04-19T09:39:30Z-
dc.date.issued2013-
dc.identifier.issn1616-5187-
dc.identifier.uri10.1002/mabi.201200308ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11315-
dc.description.abstractIntegration of biocompatible silica with a fluorescent polymer (PDDF) and superparamagnetic iron oxide nanoparticles (Fe3O4) to form uniform core-shell nanostructures has the great potential to form particles for use in multimodal bioimaging applications. Core-shell nanoparticles (PDDF/Fe3O4@SiO2) exhibit fluorescent and magnetic properties that are favorable for their use in magnetic separation and guiding applications, as well as optical and magnetic resonance (MR) imaging capabilities. With the biological analysis in an in vitro intracellular permeation and cytotoxicity test, chemical conjugation of the surface using folic acid (FA) molecules can provide the nanoparticles with cell-targeting properties, localizing the nanoparticles to folate receptors (FRs) on target KB cells that over-express the FRs.-
dc.publisherWiley-
dc.titleBifunctional nanoparticles constructed using one-pot encapsulation of a fluorescent polymer and magnetic (Fe3O4) nanoparticles in a silica shell-
dc.title.alternativeBifunctional nanoparticles constructed using one-pot encapsulation of a fluorescent polymer and magnetic (Fe3O4) nanoparticles in a silica shell-
dc.typeArticle-
dc.citation.titleMacromolecular Bioscience-
dc.citation.number3-
dc.citation.endPage331-
dc.citation.startPage321-
dc.citation.volume13-
dc.contributor.affiliatedAuthorChang-Soo Lee-
dc.contributor.affiliatedAuthorPan Kee Bae-
dc.contributor.affiliatedAuthorJuyeon Jung-
dc.contributor.affiliatedAuthorBong Hyun Chung-
dc.contributor.alternativeName이창수-
dc.contributor.alternativeName장희현-
dc.contributor.alternativeName배판기-
dc.contributor.alternativeName정주연-
dc.contributor.alternativeName정봉현-
dc.identifier.bibliographicCitationMacromolecular Bioscience, vol. 13, no. 3, pp. 321-331-
dc.identifier.doi10.1002/mabi.201200308-
dc.subject.keywordBioimaging-
dc.subject.keywordFluorescent polymers-
dc.subject.keywordMultifunctional materials-
dc.subject.keywordTumor targeting-
dc.subject.localbioimaging-
dc.subject.localBioimaging-
dc.subject.localFluorescent polymer-
dc.subject.localFluorescent polymers-
dc.subject.localMultifunctional materials-
dc.subject.localtumor targeting-
dc.subject.localTumor targeting-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
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