Polymer nanomicelles for efficient mucus delivery and antigen-specific high mucosal immunity
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Title
Polymer nanomicelles for efficient mucus delivery and antigen-specific high mucosal immunity
Author(s)
Young Woock Noh; J H Hong; Sang-Moo Shim; H S Park; H H Bae; E K Ryu; Jung Hwan Hwang; Chul Ho Lee; S H Cho; M H Sung; Haryoung Poo; Y T Lim
Bibliographic Citation
Angewandte Chemie-International Edition, vol. 52, no. 30, pp. 7684-7689
Publication Year
2013
Abstract
Micelles for mucosal immunity: A mucosal vaccine system based on γ-PGA nanomicelles and viral antigens was synthesized. The intranasal administration of the vaccine system induces a high immune response both in the humoral and cellular immunity (see picture).