Candidate target genes for the Saccharomyces cerevisiae transcription factor, Yap2

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dc.contributor.authorSeo Young Bang-
dc.contributor.authorJeong Hoon Kim-
dc.contributor.authorPhil Young Lee-
dc.contributor.authorSeung-Wook Chi-
dc.contributor.authorS Cho-
dc.contributor.authorG S Yi-
dc.contributor.authorP K Myung-
dc.contributor.authorByoung Chul Park-
dc.contributor.authorKwang-Hee Bae-
dc.contributor.authorSung Goo Park-
dc.date.accessioned2017-04-19T09:41:29Z-
dc.date.available2017-04-19T09:41:29Z-
dc.date.issued2013-
dc.identifier.issn0015-5632-
dc.identifier.uri10.1007/s12223-013-0224-zko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11426-
dc.description.abstractIn Saccharomyces cerevisiae, the Yap family of basic leucine zipper (bZip) proteins contains eight members. The Yap family proteins are implicated in a variety of stress responses; among these proteins, Yap1 acts as a major regulator of oxidative stress responses. However, the functional roles of the remaining Yap family members are poorly understood. To elucidate the function of Yap2, we mined candidate target genes of Yap2 by proteomic analysis. Among the identified genes, FRM2 was previously identified as a target gene of Yap2, which confirmed the validity of our screening method. YNL134C and YDL124W were also identified as candidate Yap2 target genes. These genes were upregulated in strains overexpressing Yap2 and possess Yap2 target sequences in their promoter regions. Furthermore, chromatin immunoprecipitation assays showed that YNL134C and YDL124W have Yap2 binding motif. These data will help to elucidate the functional role of Yap2.-
dc.publisherSpringer-
dc.titleCandidate target genes for the Saccharomyces cerevisiae transcription factor, Yap2-
dc.title.alternativeCandidate target genes for the Saccharomyces cerevisiae transcription factor, Yap2-
dc.typeArticle-
dc.citation.titleFolia Microbiologica-
dc.citation.number5-
dc.citation.endPage408-
dc.citation.startPage403-
dc.citation.volume58-
dc.contributor.affiliatedAuthorSeo Young Bang-
dc.contributor.affiliatedAuthorJeong Hoon Kim-
dc.contributor.affiliatedAuthorPhil Young Lee-
dc.contributor.affiliatedAuthorSeung-Wook Chi-
dc.contributor.affiliatedAuthorByoung Chul Park-
dc.contributor.affiliatedAuthorKwang-Hee Bae-
dc.contributor.affiliatedAuthorSung Goo Park-
dc.contributor.alternativeName방서영-
dc.contributor.alternativeName김정훈-
dc.contributor.alternativeName이필영-
dc.contributor.alternativeName지승욱-
dc.contributor.alternativeName조사연-
dc.contributor.alternativeName이관수-
dc.contributor.alternativeName명평근-
dc.contributor.alternativeName박병철-
dc.contributor.alternativeName배광희-
dc.contributor.alternativeName박성구-
dc.identifier.bibliographicCitationFolia Microbiologica, vol. 58, no. 5, pp. 403-408-
dc.identifier.doi10.1007/s12223-013-0224-z-
dc.description.journalClassY-
Appears in Collections:
Division of Biomedical Research > Disease Target Structure Research Center > 1. Journal Articles
Division of Biomedical Research > 1. Journal Articles
Critical Diseases Diagnostics Convergence Research Center > 1. Journal Articles
Division of Biomedical Research > Metabolic Regulation Research Center > 1. Journal Articles
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