An approach for simultaneous determination for geographical origins of Korean Panax ginseng by UPLC-QTOF/MS coupled with OPLS-DA models = 고려인삼의 원산지 복수 판별 방식

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Title
An approach for simultaneous determination for geographical origins of Korean Panax ginseng by UPLC-QTOF/MS coupled with OPLS-DA models = 고려인삼의 원산지 복수 판별 방식
Author(s)
Hyuk Hwan Song; Doo-Young Kim; Soyeun Woo; Hyeong Kyu Lee; Sei-Ryang Oh
Bibliographic Citation
Journal of Ginseng Research, vol. 37, no. 3, pp. 341-348
Publication Year
2013
Abstract
Identification of the origins of Panax ginseng has been issued in Korea scientifically and economically. We describe a metabolomics approach used for discrimination and prediction of ginseng roots from different origins in Korea. The fresh ginseng roots from six ginseng cooperative associations (Gangwon, Gaeseong, Punggi, Chungbuk, Jeonbuk, and Anseong) were analyzed by UPLC-MS-based approach combined with orthogonal projections to latent structure-discriminant analysis multivariate analysis. The ginsengs from Gangwon and Gaeseong were easily differentiated. We further analyzed the metabolomics results in subgroups. Punggi, Chungbuk, Jeonbuk, and Anseong ginseng could be easily differentiated by the first two orthogonal components. As a validation of the discrimination model, we performed blind prediction tests of sample origins using an external test set. Our model predicted their geographical origins as 99.7% probability. The robust discriminatory power and statistical validity of our method suggest its general applicability for determining the origins of P. ginseng samples.
Keyword
Discrimination of originsMetabolomicsOrthogonal projections to latent structure-discriminant analysisPanax ginseng
ISSN
1226-8453
Publisher
Korea Soc-Assoc-Inst
DOI
http://dx.doi.org/10.5142/jgr.2013.37.341
Type
Article
Appears in Collections:
Ochang Branch Institute > 1. Journal Articles
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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