The use of an engineered single chain variable fragment in a localized surface plasmon resonance method for analysis of the C-reactive protein

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Title
The use of an engineered single chain variable fragment in a localized surface plasmon resonance method for analysis of the C-reactive protein
Author(s)
Ju Young ByunYong Beom Shin; T Li; J H Park; D M Kim; D H Choi; M G Kim
Bibliographic Citation
Chemical Communications, vol. 49, no. 82, pp. 9497-9499
Publication Year
2013
Abstract
A gold nanorod (GNR) based LSPR sensor has been developed for label-free detection of C-reactive protein (CRP). The sensor utilizes a single chain variable fragment (scFv) as a receptor to bind CRP. The results of this effort show that CRP in human serum can be quantitatively detected at lower than 1 ng mL-1.
ISSN
1359-7345
Publisher
Royal Soc Chem
DOI
http://dx.doi.org/10.1039/c3cc45046e
Type
Article
Appears in Collections:
Division of Biomaterials Research > Bionanotechnology Research Center > 1. Journal Articles
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