Randomized double-blind placebo-controlled trial of powdered Brassica rapa ethanol extract on alteration of body composition and plasma lipid and adipocytokine profiles in overweight subjects

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dc.contributor.authorS M Jeon-
dc.contributor.authorJ E Kim-
dc.contributor.authorS K Shin-
dc.contributor.authorE Y Kwon-
dc.contributor.authorU J Jung-
dc.contributor.authorN I Baek-
dc.contributor.authorK T Lee-
dc.contributor.authorTae Sook Jeong-
dc.contributor.authorH G Chung-
dc.contributor.authorM S Choi-
dc.date.accessioned2017-04-19T09:45:19Z-
dc.date.available2017-04-19T09:45:19Z-
dc.date.issued2013-
dc.identifier.issn1096620X-
dc.identifier.uri10.1089/jmf.2012.2249ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11588-
dc.description.abstractWe evaluated the effects of Brassica rapa ethanol extract (BREE) on body composition and plasma lipid profiles through a randomized, double-blind, and placebo-controlled trial in overweight subjects. Fifty-eight overweight participants (age 20-50 years, body mass index23.0-24.9) were randomly assigned to two groups and served BREE (2 g/day) or placebo (starch, 2 g/day) for 10 weeks. Body compositions, nutrients intake, plasma lipids, adipocytokines, and hepatotoxicity biomarkers were assessed in all subjects at baseline and after 10 weeks of supplementation. The plasma total cholesterol (total-C) concentration was significantly increased after 10 weeks compared to the baseline in both groups. However, BREE supplementation significantly increased the high-density lipoprotein cholesterol (HDL-C) concentration and significantly reduced the total-C/HDL-C ratio, free fatty acid, and adipsin levels after 10 weeks. No significant differences were observed in body compositions, fasting blood glucose, plasma adipocytokines except adipsin, and aspartate aminotransferase and alanine aminotransferase activities between before and after trial within groups as well as between the two groups. The supplementation of BREE partially improves plasma lipid metabolism in overweight subjects without adverse effects.-
dc.publisherMary Ann Liebert, Inc-
dc.titleRandomized double-blind placebo-controlled trial of powdered Brassica rapa ethanol extract on alteration of body composition and plasma lipid and adipocytokine profiles in overweight subjects-
dc.title.alternativeRandomized double-blind placebo-controlled trial of powdered Brassica rapa ethanol extract on alteration of body composition and plasma lipid and adipocytokine profiles in overweight subjects-
dc.typeArticle-
dc.citation.titleJournal of Medicinal Food-
dc.citation.number2-
dc.citation.endPage138-
dc.citation.startPage133-
dc.citation.volume16-
dc.contributor.affiliatedAuthorTae Sook Jeong-
dc.contributor.alternativeName전선민-
dc.contributor.alternativeName김지은-
dc.contributor.alternativeName신수경-
dc.contributor.alternativeName권은영-
dc.contributor.alternativeName정은주-
dc.contributor.alternativeName백남인-
dc.contributor.alternativeName이경태-
dc.contributor.alternativeName정태숙-
dc.contributor.alternativeName정해건-
dc.contributor.alternativeName최명숙-
dc.identifier.bibliographicCitationJournal of Medicinal Food, vol. 16, no. 2, pp. 133-138-
dc.identifier.doi10.1089/jmf.2012.2249-
dc.subject.keywordbody composition-
dc.subject.keywordhumans-
dc.subject.keywordlipids-
dc.subject.localbody composition-
dc.subject.localhumans-
dc.subject.localhuman-
dc.subject.locallipids-
dc.subject.locallipid-
dc.description.journalClassY-
Appears in Collections:
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
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