Optimized production of 2,3-butanediol by a lactate dehydrogenase-deficient mutant of Klebsiella pneumoniae = Lactate dehydrogenase 결손 Klebsiella pneumoniae를 사용한 2,3-Butanediol 최적 생산

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dc.contributor.authorS B Lee-
dc.contributor.authorBaek Rock Oh-
dc.contributor.authorJang Min Park-
dc.contributor.authorA Yu-
dc.contributor.authorSun-Yeon Heo-
dc.contributor.authorWon-Kyung Hong-
dc.contributor.authorJeong-Woo Seo-
dc.contributor.authorChul Ho Kim-
dc.date.accessioned2017-04-19T09:50:41Z-
dc.date.available2017-04-19T09:50:41Z-
dc.date.issued2013-
dc.identifier.issn1226-8372-
dc.identifier.uri10.1007/s12257-013-0396-zko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/11815-
dc.description.abstractTo obtain high-yield production of 2,3-butanediol (2,3-BD) from glucose, we optimized the culture conditions for a lactate dehydrogenase-deficient mutant (ΔldhA) of Klebsiella pneumoniae using response surface methodology. 2,3-BD production was successfully improved by optimizing pH (5.6), aeration (3.50 vvm) and concentration of corn steep liquor (45.0 mL/L) as a nitrogen source, resulting in a maximum level of 2,3-BD production of 148.8 g/L and productivity of 2.48 g/L/h. 2,3-BD was also obtained with high concentration (76.24 g/L) and productivity (2.31 g/L/h) from the K. pneumoniae mutant strain using sugarcane molasses as a carbon source.-
dc.publisherSpringer-
dc.titleOptimized production of 2,3-butanediol by a lactate dehydrogenase-deficient mutant of Klebsiella pneumoniae = Lactate dehydrogenase 결손 Klebsiella pneumoniae를 사용한 2,3-Butanediol 최적 생산-
dc.title.alternativeOptimized production of 2,3-butanediol by a lactate dehydrogenase-deficient mutant of Klebsiella pneumoniae-
dc.typeArticle-
dc.citation.titleBiotechnology and Bioprocess Engineering-
dc.citation.number0-
dc.citation.endPage1215-
dc.citation.startPage1210-
dc.citation.volume18-
dc.contributor.affiliatedAuthorBaek Rock Oh-
dc.contributor.affiliatedAuthorJang Min Park-
dc.contributor.affiliatedAuthorSun-Yeon Heo-
dc.contributor.affiliatedAuthorWon-Kyung Hong-
dc.contributor.affiliatedAuthorJeong-Woo Seo-
dc.contributor.affiliatedAuthorChul Ho Kim-
dc.contributor.alternativeName이성목-
dc.contributor.alternativeName오백록-
dc.contributor.alternativeName박장민-
dc.contributor.alternativeName유안나-
dc.contributor.alternativeName허선연-
dc.contributor.alternativeName홍원경-
dc.contributor.alternativeName서정우-
dc.contributor.alternativeName김철호-
dc.identifier.bibliographicCitationBiotechnology and Bioprocess Engineering, vol. 18, pp. 1210-1215-
dc.identifier.doi10.1007/s12257-013-0396-z-
dc.subject.keyword2,3-butanediol-
dc.subject.keywordKlebsiella pneumoniae-
dc.subject.keywordlactate dehydrogenasedeficient mutant-
dc.subject.keywordresponse surface methodology-
dc.subject.keywordsugarcane molasses-
dc.subject.local2, 3-butanediol-
dc.subject.local2,3-Butanediol-
dc.subject.local2,3-butanediol-
dc.subject.local2,3-butanediol (2,3-BD)-
dc.subject.localKlebsiella pneumonia-
dc.subject.localKlebsiella pneumoniae-
dc.subject.locallactate dehydrogenasedeficient mutant-
dc.subject.localResponse-surface methodology-
dc.subject.localresponse surface methodology-
dc.subject.localResponse surface methodology-
dc.subject.localResponse Surface Methodology (RSM)-
dc.subject.localsugarcane molasses-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
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