Vinylogous N,N-dimethylaminomethylenation of 3-[(1-substituted)ethylidene]- oxindoles with N,N-dimethylformamide dimethylacetal

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Title
Vinylogous N,N-dimethylaminomethylenation of 3-[(1-substituted)ethylidene]- oxindoles with N,N-dimethylformamide dimethylacetal
Author(s)
H J Lee; Sangku Lee; J Yu; J N Kim
Bibliographic Citation
Tetrahedron Letters, vol. 55, no. 15, pp. 2450-2454
Publication Year
2014
Abstract
An efficient stereoselective synthesis of various 3-(3-dimethylaminoprop-2- enylidene)oxindoles has been disclosed. The compounds were synthesized via a vinylogous N,N-dimethylaminomethylenation at the γ-position of 3-[(1-substituted)ethylidene]oxindoles with DMF-DMA.
Keyword
3-AlkylideneoxindolesDMF-DMAStereoselectiveVinylogous N,N-dimethylaminomethylenation
ISSN
0040-4039
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/j.tetlet.2014.02.130
Type
Article
Appears in Collections:
Ochang Branch Institute > Anticancer Agent Research Center > 1. Journal Articles
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