Genomic encyclopedia of bacteria and archaea : sequencing a myriad of type strains

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Title
Genomic encyclopedia of bacteria and archaea : sequencing a myriad of type strains
Author(s)
N C Kyrpides; P Hugenholtz; J A Eisen; T Woyke; M Goker; C T Parker; R Amann; B J Beck; P S G Chain; J Chun; R R Colwell; A Danchin; P Dawyndt; T Dedeurwaerdere; E F DeLong; J C Detter; P D Vos; T J Donohue; X Z Dong; D S Ehrlich; C Fraser; R Gibbs; J Gilbert; Jung-Sook Lee; H P Klenk
Bibliographic Citation
PLoS Biology, vol. 12, no. 8, pp. 1001920-1001920
Publication Year
2014
Abstract
Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.
ISSN
1544-9173
Publisher
Public Library of Science
DOI
http://dx.doi.org/10.1371/journal.pbio.1001920
Type
Article
Appears in Collections:
Jeonbuk Branch Institute > Biological Resource Center > 1. Journal Articles
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