Evolution and ecology of influenza A viruses

Cited 242 time in scopus
Metadata Downloads
Title
Evolution and ecology of influenza A viruses
Author(s)
Sun Woo Yoon; R J Webby; R G Webster
Bibliographic Citation
Current Topics in Microbiology and Immunology, vol. 385, pp. 359-375
Publication Year
2014
Abstract
Wild aquatic bird populations have long been considered the natural reservoir for influenza A viruses with virus transmission from these birds seeding other avian and mammalian hosts. While most evidence still supports this dogma, recent studies in bats have suggested other reservoir species may also exist. Extensive surveillance studies coupled with an enhanced awareness in response to H5N1 and pandemic 2009 H1N1 outbreaks is also revealing a growing list of animals susceptible to infection with influenza A viruses. Although in a relatively stable host?pathogen interaction in aquatic birds, antigenic, and genetic evolution of influenza A viruses often accompanies interspecies transmission as the virus adapts to a new host. The evolutionary changes in the new hosts result from a number of processes including mutation, reassortment, and recombination. Depending on host and virus these changes can be accompanied by disease outbreaks impacting wildlife, veterinary, and public health.
ISSN
0070-217X
Publisher
Springer
DOI
http://dx.doi.org/10.1007/82_2014_396
Type
Article
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.