Cytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.

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dc.contributor.authorY J Lee-
dc.contributor.authorJ W Lee-
dc.contributor.authorD G Lee-
dc.contributor.authorH S Lee-
dc.contributor.authorJong Soon Kang-
dc.contributor.authorJi Eun Yun-
dc.date.accessioned2017-04-19T09:57:53Z-
dc.date.available2017-04-19T09:57:53Z-
dc.date.issued2014-
dc.identifier.issn1422-0067-
dc.identifier.uri10.3390/ijms151120045ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/12252-
dc.description.abstractEight scalarane sesterterpenoids, including four new compounds, were isolated from the marine sponge Scalarispongia sp. The structures of the new compounds were elucidated by 2D-NMR and HRMS analyses. All of the isolated compounds, with the exception of 16-O-deacetyl-12,16-epi-scalarolbutanolide, showed significant in vitro cytotoxicity (GI50 values down to 5.2 μM) against six human cancer cell lines.-
dc.publisherMDPI-
dc.titleCytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.-
dc.title.alternativeCytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.-
dc.typeArticle-
dc.citation.titleInternational Journal of Molecular Sciences-
dc.citation.number11-
dc.citation.endPage20053-
dc.citation.startPage20045-
dc.citation.volume15-
dc.contributor.affiliatedAuthorJong Soon Kang-
dc.contributor.affiliatedAuthorJi Eun Yun-
dc.contributor.alternativeName이연주-
dc.contributor.alternativeName이정우-
dc.contributor.alternativeName이동근-
dc.contributor.alternativeName이희승-
dc.contributor.alternativeName강종순-
dc.contributor.alternativeName윤지은-
dc.identifier.bibliographicCitationInternational Journal of Molecular Sciences, vol. 15, no. 11, pp. 20045-20053-
dc.identifier.doi10.3390/ijms151120045-
dc.subject.keywordCytotoxicity-
dc.subject.keywordScalarane-
dc.subject.keywordScalarispongia-
dc.subject.keywordSesterterpenoid-
dc.subject.keywordSponge-
dc.subject.localCytotoxicity-
dc.subject.localcytotoxicity-
dc.subject.localScalarane-
dc.subject.localScalarispongia-
dc.subject.localSesterterpenoid-
dc.subject.localSponge-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
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