Corilagin with inhibitory activity against NO production from Euphorbia supina

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Title
Corilagin with inhibitory activity against NO production from Euphorbia supina
Author(s)
H S Chae; Y M Kim; E J Lee; Hyuk-Hwan Song; Sei-Ryang Oh; Y H Choi; Y W Chin
Bibliographic Citation
Natural Products Sciences, vol. 20, no. 2, pp. 126-129
Publication Year
2014
Abstract
Bioactivity-guided investigation on whole plant of Euphorbia supina, using LPS-induced Raw264.7 cells, led to the identificaiton of a tannin which was not reported from this plant along with four known constituents (quercetin, astragalin, juglanin and methyl gallate). The structure of the tannin was determined as corilagin by the interpretation of NMR (1D and 2D) and MS spectroscopic data. All the isolates were tested for the inhibitory activity against NO production in LPS-induced Raw264.7 cells. Among the tested isolates, corilagin was found to be the most active compound
Keyword
CorilaginEuphorbia supinaEuphorbiaceaeNitric oxideTannin
ISSN
I000-0147
Publisher
Korean Society of Pharmacognosy
Type
Article
Appears in Collections:
Ochang Branch Institute > 1. Journal Articles
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