Smart nanoprobes for the detection of alkaline phosphatase activity during osteoblast differentiation

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dc.contributor.authorEun Kyung Lim-
dc.contributor.authorJoo Oak Keem-
dc.contributor.authorH S Yun-
dc.contributor.authorJin Young Jeong-
dc.contributor.authorBong Hyun Chung-
dc.date.accessioned2017-04-19T10:01:48Z-
dc.date.available2017-04-19T10:01:48Z-
dc.date.issued2015-
dc.identifier.issn1359-7345-
dc.identifier.uri10.1039/c4cc09620gko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/12445-
dc.description.abstractGold nanoparticle-conjugated fluorescent hydroxyapatite (AuFHAp) was developed as a smart nanoprobe for measuring alkaline phosphatase (ALP) activity. AuFHAp showed NIR fluorescence due to the hydrolysis of its phosphate groups by ALP. In addition, gold nanoparticles help reduce the nonspecific signal by absorbing nonspecific fluorescence. Through in vitro tests, we confirmed that the AuFHAp probe was capable of detecting ALP levels related to osteoblast activity in living cells with high fluorescence intensity.-
dc.publisherRoyal Soc Chem-
dc.titleSmart nanoprobes for the detection of alkaline phosphatase activity during osteoblast differentiation-
dc.title.alternativeSmart nanoprobes for the detection of alkaline phosphatase activity during osteoblast differentiation-
dc.typeArticle-
dc.citation.titleChemical Communications-
dc.citation.number15-
dc.citation.endPage3272-
dc.citation.startPage3270-
dc.citation.volume51-
dc.contributor.affiliatedAuthorEun Kyung Lim-
dc.contributor.affiliatedAuthorJoo Oak Keem-
dc.contributor.affiliatedAuthorJin Young Jeong-
dc.contributor.affiliatedAuthorBong Hyun Chung-
dc.contributor.alternativeName임은경-
dc.contributor.alternativeName김주옥-
dc.contributor.alternativeName윤희숙-
dc.contributor.alternativeName정진영-
dc.contributor.alternativeName정봉현-
dc.identifier.bibliographicCitationChemical Communications, vol. 51, no. 15, pp. 3270-3272-
dc.identifier.doi10.1039/c4cc09620g-
dc.description.journalClassY-
Appears in Collections:
Division of Research on National Challenges > Bionanotechnology Research Center > 1. Journal Articles
Division of Research on National Challenges > Environmental diseases research center > 1. Journal Articles
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