Recent advances in proteomic studies of adipose tissues and adipocytes

Cited 23 time in scopus
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Title
Recent advances in proteomic studies of adipose tissues and adipocytes
Author(s)
Eun Young Kim; Won Kon KimKyoung Jin OhBaek Soo HanSang Chul LeeKwang-Hee Bae
Bibliographic Citation
International Journal of Molecular Sciences, vol. 16, pp. 4581-4599
Publication Year
2015
Abstract
Obesity is a chronic disease that is associated with significantly increased levels of risk of a number of metabolic disorders. Despite these enhanced health risks, the worldwide prevalence of obesity has increased dramatically over the past few decades. Obesity is caused by the accumulation of an abnormal amount of body fat in adipose tissue, which is composed mostly of adipocytes. Thus, a deeper understanding of the regulation mechanism of adipose tissue and/or adipocytes can provide a clue for overcoming obesity-related metabolic diseases. In this review, we describe recent advances in the study of adipose tissue and/or adipocytes, focusing on proteomic approaches. In addition, we suggest future research directions for proteomic studies which may lead to novel treatments of obesity and obesity-related diseases.
Keyword
adipocytesadipogenesisadipose tissuebrowningproteomics
ISSN
1422-0067
Publisher
MDPI
DOI
http://dx.doi.org/10.3390/ijms16034581
Type
Article
Appears in Collections:
Division of Biomedical Research > Metabolic Regulation Research Center > 1. Journal Articles
Division of Research on National Challenges > Biodefense Research Center > 1. Journal Articles
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