Inefficient transmissibility of NS-truncated H3N8 equine influenza virus in dogs

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Title
Inefficient transmissibility of NS-truncated H3N8 equine influenza virus in dogs
Author(s)
Woonsung Na; M Song; Minjoo Yeom; Nanuri Park; B Kang; H Moon; Dae Gwin Jeong; J K Kim; Dae Sub Song
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 25, no. 3, pp. 317-320
Publication Year
2015
Abstract
H3N8 equine influenza virus (EIV) causes respiratory diseases in the horse population, and it has been demonstrated that EIV can transmit into dogs owing to its availability on receptors of canine respiratory epithelial cells. Recently, we isolated H3N8 EIV from an EIV-vaccinated horse that showed symptoms of respiratory disease, and which has a partially truncated nonstructural gene (NS). However, it is not clear that the NS-truncated EIV has an ability to cross the host species barrier from horses to dogs as well. Here, we experimentally infected the NS-truncated H3N8 EIV into dogs, and monitored their clinical signs and viral load in respiratory organs to determine the virus’s transmissibility.
Keyword
H3N8 EIVNS truncationTransmission
ISSN
1017-7825
Publisher
South Korea
DOI
http://dx.doi.org/10.4014/jmb.1409.09078
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
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