DC Field | Value | Language |
---|---|---|
dc.contributor.author | C H Park | - |
dc.contributor.author | J E Park | - |
dc.contributor.author | T S Kim | - |
dc.contributor.author | Y H Kang | - |
dc.contributor.author | Nak Kyun Soung | - |
dc.contributor.author | M Zhou | - |
dc.contributor.author | N H Kim | - |
dc.contributor.author | J K Bang | - |
dc.contributor.author | K S Lee | - |
dc.date.accessioned | 2017-04-19T10:02:48Z | - |
dc.date.available | 2017-04-19T10:02:48Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0021-9258 | - |
dc.identifier.uri | 10.1074/jbc.M114.623546 | ko |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/12534 | - |
dc.description.abstract | Background: Plk1 is a protein kinase that localizes to subcellular structures called kinetochores to promote mitotic progression. Results: Plk1 interacts with and regulates a kinetochore-associated PBIP1·CENP-Q complex. Conclusion: This is a tightly regulated, cell cycle-dependent process, the deregulation of which leads to improper chromosome segregation and mitotic progression. Significance: This event is likely critical for maintaining genomic integrity and preventing aneuploidy. | - |
dc.publisher | Amer Soc Biochemistry Molecular Biology Inc | - |
dc.title | Mammalian polo-like Kinase 1 (Plk1) promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1·CENP-Q complex from kinetochores | - |
dc.title.alternative | Mammalian polo-like Kinase 1 (Plk1) promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1·CENP-Q complex from kinetochores | - |
dc.type | Article | - |
dc.citation.title | Journal of Biological Chemistry | - |
dc.citation.number | 13 | - |
dc.citation.endPage | 8581 | - |
dc.citation.startPage | 8569 | - |
dc.citation.volume | 290 | - |
dc.contributor.affiliatedAuthor | Nak Kyun Soung | - |
dc.contributor.alternativeName | 박치훈 | - |
dc.contributor.alternativeName | 박정은 | - |
dc.contributor.alternativeName | 김태성 | - |
dc.contributor.alternativeName | 강영휘 | - |
dc.contributor.alternativeName | 성낙균 | - |
dc.contributor.alternativeName | Zhou | - |
dc.contributor.alternativeName | 김남형 | - |
dc.contributor.alternativeName | 방정규 | - |
dc.contributor.alternativeName | 이경상 | - |
dc.identifier.bibliographicCitation | Journal of Biological Chemistry, vol. 290, no. 13, pp. 8569-8581 | - |
dc.identifier.doi | 10.1074/jbc.M114.623546 | - |
dc.description.journalClass | Y | - |
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