Nanomaterials for enhanced immunity as an innovative paradigm in nanomedicine

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Title
Nanomaterials for enhanced immunity as an innovative paradigm in nanomedicine
Author(s)
A Seth; Doo-Byoung Oh; Y T Lim
Bibliographic Citation
Nanomedicine, vol. 10, no. 6, pp. 959-975
Publication Year
2015
Abstract
Since the advent of nanoparticle technology, novel and versatile properties of nanomaterials have been introduced, which has constantly expanded their applications in therapeutics. Introduction of nanomaterials for immunomodulation has opened up new avenues with tremendous potential. Interesting properties of nanoparticles, such as adjuvanticity, capability to enhance cross-presentation, polyvalent presentation, siRNA delivery for silencing of immunesuppressive gene, targeting and imaging of immune cells have been known to have immense utility in vaccination and immunotherapy. A thorough understanding of the merits associated with nanomaterials is crucial for designing of modular and versatile nanovaccines, for improved immune response. With the emerging prerequisites of vaccination, nanomaterial-based immune stimulation, seems to be capable of taking the field of immunization to a next higher level.
Keyword
adjuvantantigenantigen presenting cellscross-presentationimmune responsenanoparticlevaccine
ISSN
1743-5889
Publisher
Future Medicine Ltd
DOI
http://dx.doi.org/10.2217/nnm.14.200
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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