Surface plasmon resonance: a versatile technique for biosensor applications

Cited 604 time in scopus
Metadata Downloads
Title
Surface plasmon resonance: a versatile technique for biosensor applications
Author(s)
H H Nguyen; Jeho Park; S Kang; Moonil Kim
Bibliographic Citation
Sensors, vol. 15, no. 5, pp. 10481-10510
Publication Year
2015
Abstract
Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.
Keyword
ApplicationsBiosensorSPRSPR imagingSurface plasmon resonance
ISSN
1424-8220
Publisher
MDPI
DOI
http://dx.doi.org/10.3390/s150510481
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:

Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.