Strategies in protein immobilization on a gold surface

Cited 0 time in scopus
Metadata Downloads
Strategies in protein immobilization on a gold surface
Jeho Park; Moonil Kim
Bibliographic Citation
Applied Science and Convergence Technology, vol. 24, no. 1, pp. 1-8
Publication Year
Protein immobilization on a gold surface plays an important role in the usefulness of biosensors that utilize gold-coated surfaces such as surface plasmon resonance (SPR), quartz crystal microbalance (QCM), etc. For developing high performance biosensors, it is necessarily required that immobilized proteins must remain biologically active. Loss of protein activity and maintenance of its stability on transducer surfaces is directly associated with the choice of immobilization methods, affecting protein-protein interactions. During the past decade, a variety of strategies have been extensively developed for the effective immobilization of proteins in terms of the orientation, density, and stability of immobilized proteins on analytical devices operating on different principles. In this review, recent advances and novel strategies in protein immobilization technologies developed for biosensors are briefly discussed, thereby providing an useful information for the selection of appropriate immobilization approach.
Protein immobilizationBiosensorGold surfaceOrientationImmobilization technique
Korea Soc-Assoc-Inst
Appears in Collections:
Critical Diseases Diagnostics Convergence Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.

Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.