Suvanine analogs from a Coscinoderma sp. marine sponge and their cytotoxicities against human cancer cell lines

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Title
Suvanine analogs from a Coscinoderma sp. marine sponge and their cytotoxicities against human cancer cell lines
Author(s)
J W Lee; H S Lee; J Shin; Jong Soon Kang; Jieun Yun; H J Shin; J S Lee; Y J Lee
Bibliographic Citation
Archives of Pharmacal Research, vol. 38, no. 6, pp. 1005-1010
Publication Year
2015
Abstract
Nine suvanine analogs including suvanine phenethylammonium salt and two new compounds were isolated from the marine sponge Coscinoderma sp., collected from Chuuk State, Federated States of Micronesia. The structures of the new compounds were elucidated by 2D NMR and HRMS analyses. Suvanine and a new analog exhibited weak but selective cytotoxicity against colon (HCT-15), lung (NCI-H23), stomach (NUGC-3), and prostate (PC-3) cancer cell lines.
Keyword
CoscinodermaCytotoxicityHuman cancer cell lineMarine spongeSulfated sesterterpenoidSuvanine
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/s12272-014-0479-1
Type
Article
Appears in Collections:
Ochang Branch Institute > Division of Bioinfrastructure > Laboratory Animal Resource Center > 1. Journal Articles
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