Network comparison of inflammation in colorectal cancer and Alzheimer's disease

Cited 2 time in scopus
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dc.contributor.authorS Park-
dc.contributor.authorS J Yu-
dc.contributor.authorY Cho-
dc.contributor.authorC Balch-
dc.contributor.authorJinhyuk Lee-
dc.contributor.authorY H Kim-
dc.contributor.authorS Nam-
dc.date.accessioned2017-04-19T10:09:56Z-
dc.date.available2017-04-19T10:09:56Z-
dc.date.issued2015-
dc.identifier.issn23146133-
dc.identifier.uri10.1155/2015/205247ko
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/12777-
dc.description.abstractRecently, a large clinical study revealed an inverse correlation of individual risk of cancer versus Alzheimer's disease (AD). However, no explanation exists for this anticorrelation at the molecular level; however, inflammation is crucial to the pathogenesis of both diseases, necessitating a need to understand differing signaling usage during inflammatory responses distinct to both diseases. Using a subpathway analysis approach, we identified numerous well-known and previously unknown pathways enriched in datasets from both diseases. Here, we present the quantitative importance of the inflammatory response in the two disease pathologies and summarize signal transduction pathways common to both diseases that are affected by inflammation.-
dc.publisherHindawi Ltd-
dc.titleNetwork comparison of inflammation in colorectal cancer and Alzheimer's disease-
dc.title.alternativeNetwork comparison of inflammation in colorectal cancer and Alzheimer's disease-
dc.typeArticle-
dc.citation.titleBiomed Research International-
dc.citation.number0-
dc.citation.endPage205247-
dc.citation.startPage205247-
dc.citation.volume2015-
dc.contributor.affiliatedAuthorJinhyuk Lee-
dc.contributor.alternativeName박성진-
dc.contributor.alternativeName유석종-
dc.contributor.alternativeName조용성-
dc.contributor.alternativeNameBalch-
dc.contributor.alternativeName이진혁-
dc.contributor.alternativeName김연희-
dc.contributor.alternativeName남승윤-
dc.identifier.bibliographicCitationBiomed Research International, vol. 2015, pp. 205247-205247-
dc.identifier.doi10.1155/2015/205247-
dc.description.journalClassY-
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Division of Biomedical Research > Genome Editing Research Center > 1. Journal Articles
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