A reusable Pb2+ detecting aptasensor employing a gold nanorod-DNAzyme conjugate = 재사용이 가능한 납이온 검출을 위한 금나노막대-DNAzyme 컨쥬게이트

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Title
A reusable Pb2+ detecting aptasensor employing a gold nanorod-DNAzyme conjugate = 재사용이 가능한 납이온 검출을 위한 금나노막대-DNAzyme 컨쥬게이트
Author(s)
Jayeon Lee; Tai Hwan Ha
Bibliographic Citation
Applied Science and Convergence Technology, vol. 24, no. 5, pp. 190-195
Publication Year
2015
Abstract
Here, we demonstrated a Pb2+ detecting aptasensor using Pb2+-sensitive DNAzymeconjugated gold nanorods (GNRs). Fluorescent DNA substrates that were initially quenched by GNRs, are released in response to Pb2+ ions to give a substantial fluorescence signal. The GNR-tethered DNAzyme is reusable at least three times with a LOD of 50 nM.
Keyword
DNAzymeHeavy metal ionsGold nanorodAptamer
ISSN
2288-6559
Publisher
Korea Soc-Assoc-Inst
Full Text Link
http://dx.doi.org/10.5757/ASCT.2015.24.5.190
Type
Article
Appears in Collections:
Division of Bio Technology Innovation > Core Research Facility & Analysis Center > 1. Journal Articles
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