Inhibition effect of neo-lignans from Eleutherococcus senticosus (Rupt. & Maxim.) Maxim on diacylglycerol acyltransferase (DGAT)
Cited 9 time in 
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | J L Li | - |
| dc.contributor.author | N Li | - |
| dc.contributor.author | Hyun Sun Lee | - |
| dc.contributor.author | S S Xing | - |
| dc.contributor.author | S Z Qi | - |
| dc.contributor.author | Z D Tuo | - |
| dc.contributor.author | L Zhang | - |
| dc.contributor.author | X B Wang | - |
| dc.contributor.author | L Cui | - |
| dc.date.accessioned | 2017-04-19T10:16:32Z | - |
| dc.date.available | 2017-04-19T10:16:32Z | - |
| dc.date.issued | 2016 | - |
| dc.identifier.issn | 1874-3900 | - |
| dc.identifier.uri | 10.1016/j.phytol.2015.12.012 | ko |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/13088 | - |
| dc.description.abstract | Two new neo-lignans, erythro-7E-4′,9′-dihydroxy-4,5′-dimethoxy-5,8′-oxyneolign-7-en-9-al (1) and 4,5′-dimethoxy-lariciresinol (2) together with five known compounds (3-7) were isolated from the EtOAc-soluble extract of Eleutherococcus senticosus (Rupt. & Maxim.) Maxim, and their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All the isolates were evaluated for in vitro inhibitory activity against DGAT1 and DGAT2. Among them, compounds 1 and 3-6 were found to exhibit selective inhibitory activity on DGAT1 with IC50 values ranging from 66.5 ± 1.3 to 111.1 ± 1.4 μM. | - |
| dc.publisher | Elsevier | - |
| dc.title | Inhibition effect of neo-lignans from Eleutherococcus senticosus (Rupt. & Maxim.) Maxim on diacylglycerol acyltransferase (DGAT) | - |
| dc.title.alternative | Inhibition effect of neo-lignans from Eleutherococcus senticosus (Rupt. & Maxim.) Maxim on diacylglycerol acyltransferase (DGAT) | - |
| dc.type | Article | - |
| dc.citation.title | Phytochemistry Letters | - |
| dc.citation.number | 0 | - |
| dc.citation.endPage | 151 | - |
| dc.citation.startPage | 147 | - |
| dc.citation.volume | 15 | - |
| dc.contributor.affiliatedAuthor | Hyun Sun Lee | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | Li | - |
| dc.contributor.alternativeName | 이현선 | - |
| dc.contributor.alternativeName | - | |
| dc.contributor.alternativeName | Qi | - |
| dc.contributor.alternativeName | Tuo | - |
| dc.contributor.alternativeName | Zhang | - |
| dc.contributor.alternativeName | Wang | - |
| dc.contributor.alternativeName | Cui | - |
| dc.identifier.bibliographicCitation | Phytochemistry Letters, vol. 15, pp. 147-151 | - |
| dc.identifier.doi | 10.1016/j.phytol.2015.12.012 | - |
| dc.subject.keyword | Araliaceae | - |
| dc.subject.keyword | DGAT | - |
| dc.subject.keyword | Eleutherococcus senticosus (Rupt. & | - |
| dc.subject.keyword | Maxim.) Maxim | - |
| dc.subject.keyword | Neo-lignans | - |
| dc.subject.local | araliaceae | - |
| dc.subject.local | Araliaceae | - |
| dc.subject.local | DGAT | - |
| dc.subject.local | Eleutherococcus senticosus (Rupt. & Maxim.) Maxim | - |
| dc.subject.local | Eleutherococcus senticosus (Rupt. & | - |
| dc.subject.local | Eleutherococcus senticosus (Rupt. & Maxim.) | - |
| dc.subject.local | Eleutherococcus senticosus | - |
| dc.subject.local | Maxim.) Maxim | - |
| dc.subject.local | Neolignans | - |
| dc.subject.local | Neo-lignan | - |
| dc.subject.local | Neo-lignans | - |
| dc.subject.local | neolignan | - |
| dc.subject.local | Neolignan | - |
| dc.description.journalClass | Y | - |
- Appears in Collections:
- Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
- Files in This Item:
There are no files associated with this item.
Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.