Identification of bitter components from Artemisia princeps Pamp.

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Title
Identification of bitter components from Artemisia princeps Pamp.
Author(s)
H J Park; J G Cho; Y S Baek; K H Seo; S Y Kim; M S Choi; K T Lee; Tae Sook Jeong; H G Chung; E G Kang; N I Baek
Bibliographic Citation
Food Science and Biotechnology, vol. 25, no. 1, pp. 27-32
Publication Year
2016
Abstract
Identification of bitter components from the aerial parts of Artemisia princeps Pamp. was performed to search for a method to eliminate the bitter taste from A. princeps products. The aerial parts of A. princeps were extracted in an aqueous EtOH solution, and the obtained extracts were partitioned into essential-oil, flavonoid-rich, n-BuOH, and aqueous fractions. Two purified bitter sesquiterpenoids were identified through repeated column chromatography of the bitterest fraction, the flavonoid-rich fraction, through an activity-guided fractionation method. The compounds were identified to be 1α,6α,8α-trihydroxy-5α,7βH-guaia-3,9,11(13)-trien-12-oic acid and artecalin, respectively, based on the interpretation of NMR, MS, and IR spectroscopic data. Both compounds were 50 times bitterer than caffeine and had similar bitterness to quinine HCl. Neither eupatilin nor jaceosidin, the major active components of A. princeps, showed any bitterness.
Keyword
1α,6α,8α-trihydroxy-5α,7βH-guaia-3,9,11(13)-trien-12-oic acidartecalinArtemisia princepsbitterness
ISSN
1226-7708
Publisher
South Korea
DOI
http://dx.doi.org/10.1007/s10068-016-0004-z
Type
Article
Appears in Collections:
Division of Biomaterials Research > Industrial Bio-materials Research Center > 1. Journal Articles
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