Open Access@KRIBBOchang Branch InstituteDivision of National Bio-InfrastructureLaboratory Animal Resource & Research Center1. Journal Articles
Lanostane triterpenes isolated from Antrodia heteromorpha and their inhibitory effects on RANKL-induced osteoclastogenesis
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- Title
- Lanostane triterpenes isolated from Antrodia heteromorpha and their inhibitory effects on RANKL-induced osteoclastogenesis
- Author(s)
- J Kwon; H Lee; Yeo Dae Yoon; B Y Hwang; Y Guo; Jong Soon Kang; J J Kim; D Lee
- Bibliographic Citation
- Journal of Natural Products, vol. 79, no. 6, pp. 1689-1693
- Publication Year
- 2016
- Abstract
- Two new spiro-lanostane triterpenoids, antrolactones A and B (1 and 2), along with polyporenic acid C (3), were isolated from an EtOAc-soluble extract of Antrodia heteromorpha culture medium, and the chemical structures of the new compounds were elucidated by application of NMR, MS, and ECD spectroscopic techniques. All isolated compounds exhibited inhibitory effects on receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis.
- ISSN
- 0163-3864
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/acs.jnatprod.6b00207
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Division of National Bio-Infrastructure > Laboratory Animal Resource & Research Center > 1. Journal Articles
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